Evidence map›Paper›PMID 38263917›Full record

ArticleLa Tunisie medicale2023

Risk of metabolic syndrome in patients with chronic hepatitis C.

Mouna Medhioub, Amal Khsiba, Asma Bachali, Amina Bibi, Lamnie Hamzaoui, Mohamed Moussadek Azouz

Abstract read
In one paragraph

Article in La Tunisie medicale, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mouna MedhioubUniversity of Tunis el Manar, Faculty of Medicine of Tunis, Gastrology Department, Mohamed Taher Maamouri Hospital, Nabeul, Tunisia.
Amal KhsibaUniversity of Tunis el Manar, Faculty of Medicine of Tunis, Gastrology Department, Mohamed Taher Maamouri Hospital, Nabeul, Tunisia.
Asma BachaliUniversity of Tunis el Manar, Faculty of Medicine of Tunis, Biochemistry Laboratory, Mohamed Taher Maamouri Hospital, Nabeul, Tunisia.
Amina BibiUniversity of Tunis el Manar, Faculty of Medicine of Tunis, Clinical Biology Laboratory, Institute of Nutrition and Food Technology, Tunis, Tunisia.
Lamnie HamzaouiUniversity of Tunis el Manar, Faculty of Medicine of Tunis, Gastrology Department, Mohamed Taher Maamouri Hospital, Nabeul, Tunisia.
Mohamed Moussadek AzouzUniversity of Tunis el Manar, Faculty of Medicine of Tunis, Gastrology Department, Mohamed Taher Maamouri Hospital, Nabeul, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic hepatitis C is associated with several metabolic abnormalities including diabetes and insulin resistance. Metabolic syndrome, a major cardiovascular risk factor, may represent an additional risk of morbidity and mortality in patients with viral hepatitis C.

aimTo assess the risk of metabolic syndrome in patients with chronic hepatitis C and its impact on liver fibrosis.

methodsRetrospective cohort study, including a group of exposed patients with untreated chronic hepatitis C and a group of unexposed patients with negative hepatitis C serology. We compared the prevalence of metabolic syndrome between the two groups and evaluated the association between metabolic syndrome and advanced fibrosis in the exposed patients.

resultsForty exposed and 40 unexposed were included. The two groups were matched for age, sex and anthropometric data. Fibrosis was significant in 67.5% of the exposed group. The exposed group had a significantly higher prevalence of metabolic syndrome and insulin resistance compared to the unexposed group (37.5% VS 15%; p=0.02 VS 67.5% , 37.5%; p=0.02 VS 67.5%, 37.5%; p=0.007, respectively). The relative risk of metabolic syndrome in the exposed group was 2.5. Metabolic syndrome was not associated with significant fibrosis (p=0.7).

Indexed as

Abnormalities, MultipleHepatitis CHepatitis C, ChronicInsulin ResistanceMetabolic SyndromeHumansLiver CirrhosisRetrospective Studies

Identifiers

PMID38263917
PMCPMC11157234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.