Evidence map›Paper›PMID 38263894›Full record

Observational studyActa obstetricia et gynecologica Scandinavica2024

Adherence to different forms of plant-based diets and pregnancy outcomes in the Danish National Birth Cohort: A prospective observational study.

Signe Hedegaard, Ellen Aagaard Nohr, Sjurdur Frodi Olsen, Thorhallur Ingvi Halldorsson, Kristina Martha Renault

Abstract readObservational Study
In one paragraph

Observational study in Acta obstetricia et gynecologica Scandinavica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A 2 year retrospective study of vegan patients and their pregnancy outcomes in a tertiary level Irish hospital.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  16. Vegetarian diet and pregnancy outcome.European journal of obstetrics & gynecology and reproductive biology: X · 2024
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  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Signe HedegaardDepartment of Obstetrics and Gynecology, Rigshospitalet, Juliane Marie Center, University of Copenhagen, Copenhagen, Denmark.ORCID 0009-0004-0150-2616
Ellen Aagaard NohrResearch Unit for Obstetrics and Gynecology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-7039-1105
Sjurdur Frodi OlsenDepartment of Epidemiologic Research, Statens Serum Institut, Copenhagen, Denmark.
Thorhallur Ingvi HalldorssonDepartment of Epidemiologic Research, Statens Serum Institut, Copenhagen, Denmark.
Kristina Martha RenaultDepartment of Obstetrics and Gynecology, Rigshospitalet, Juliane Marie Center, University of Copenhagen, Copenhagen, Denmark.

Funding

Danmarks Frie Forskningsfond DFF - 4183-00152Danmarks Frie Forskningsfond DFF- 4183-00594Danmarks GrundforskningsfondHjerteforeningenInnovationsfonden 09-067124March of Dimes Birth Defects Foundation 6-FY00-407March of Dimes Birth Defects Foundation 6-FY-96-0240March of Dimes Birth Defects Foundation 6-FY97-0521March of Dimes Birth Defects Foundation 6-FY97-0553Sundhed og Sygdom, Det Frie ForskningsrådSygekassernes Helsefond
6 · The paper itself

Abstract

introductionThe number of people adhering to plant-based diets has been increasing dramatically in recent years, fueled by both environmental and animal welfare concerns. Beneficial or possible adverse consequences of such diets, particularly the most restrictive forms during pregnancy, have been minimally explored. The aim of this prospective observational study was to examine associations between different forms of plant-based diets during pregnancy with birth outcomes and pregnancy complications. MATERIAL AND

methodsThe Danish National Birth Cohort included 100 413 pregnancies to 91 381 women in 1996-2002. The population consisted of 66 738 pregnancies, about which sufficient dietary data were available and included in the study. Dietary and supplemental intake was assessed by Food Frequency Questionnaire in gestational week 25 and women were characterized as fish/poultry-vegetarians, lacto/ovo-vegetarians, vegans or omnivorous, based on their self-report in gestational week 30. Main outcome measures were pregnancy and birth complications, birthweight and small for gestational age.

resultsA total of 98.7% (n = 65 872) of participants were defined as omnivorous, whereas 1.0% (n = 666), 0.3% (n = 183) and 0.03% (n = 18) identified themselves as fish/poultry vegetarians, lacto/ovo-vegetarians or vegans, respectively. Protein intake was lower among lacto/ovo-vegetarians (13.3%) and vegans (10.4%) than among omnivorous participants (15.4%). Intake of micronutrients was also considerably lower among vegans, but when dietary supplements were taken into consideration, no major differences were observed. Compared with omnivorous mothers, vegans had a higher prevalence of preeclampsia and their offspring had on average -240 g (95% confidence interval -450 to -30) lower birthweight.

conclusionsThe women reporting that they adhered to vegan diets during pregnancy had offspring with lower mean birthweight and higher risk of preeclampsia compared with omnivorous mothers. Low protein intake might be one plausible explanation for the observed association with birthweight.

Indexed as

Diet, VegetarianPregnancy OutcomeAdultBirth WeightCohort StudiesDenmarkDiet, Plant-BasedFemaleHumansInfant, NewbornInfant, Small for Gestational AgePregnancyPregnancy ComplicationsProspective StudiesDanish National Birth Cohortdietpregnancy outcomesvegansvegetarians

Identifiers

PMID38263894
PMCPMC11103146

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.