Evidence map›Paper›PMID 38263680›Full record

ArticleNMR in biomedicine2024

Transmembrane pH gradient imaging in rodent glioma models.

Sandeep Kumar Mishra, Jessica Gois Santana, Jelena Mihailovic, Fahmeed Hyder, Daniel Coman

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sandeep Kumar MishraDepartment of Radiology & Biomedical Imaging, Yale University, New Haven, Connecticut, USA.
Jessica Gois SantanaDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut, USA.
Jelena MihailovicDepartment of Radiology & Biomedical Imaging, Yale University, New Haven, Connecticut, USA.
Fahmeed HyderDepartment of Radiology & Biomedical Imaging, Yale University, New Haven, Connecticut, USA.
Daniel ComanDepartment of Radiology & Biomedical Imaging, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-6289-0817
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Extracellular pH mapping as therapeutic readout of drug delivery in glioblastomaR01EB023366 · NIBIB · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2017 to 2020
$2.5M
Interleaved 1H/23Na imaging for invasive and proliferative phenotypes of brain tumorsR01CA280871 · NCI · YALE UNIVERSITY · PI Dewan Syed Fahmeed Hyder · 2023 to 2026
$2.2M
Hypoxia and pH Responsive Nanoparticles for Targeted Drug Delivery to Ischemic StrokeR21NS132543 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED, SANSING, LAUREN H · 2023 to 2024
$461k
NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA280871NIBIB NIH HHS R01 EB023366NINDS NIH HHS R21 NS132543
6 · The paper itself

Abstract

A unique feature of the tumor microenvironment is extracellular acidosis in relation to intracellular milieu. Metabolic reprogramming in tumors results in overproduction of H

Indexed as

Brain NeoplasmsGliomaAnimalsBrainHydrogen-Ion ConcentrationMagnetic Resonance ImagingMiceProton-Motive ForceRatsRodentiaTumor MicroenvironmentAACIDBIRDSextracellular pHgliomaintracellular pHMRIMRSItransmembrane pH

Identifiers

PMID38263680
PMCPMC10987279
OpenAlexW4391171522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.