ArticleScientific reports2024
Arterial stiffness assessment using PPG feature extraction and significance testing in an in vitro cardiovascular system.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- Experimental Analysis on the Effect of Contact Pressure and Activity Level as Influencing Factors in PPG Sensor Performance.Sensors (Basel, Switzerland) · 2025Trial
- Development and validation of a digital biomarker for peripheral artery disease.NPJ digital medicine · 2026Article
- Multimodal assessment of arterial stiffness using photoplethysmography and laser Doppler flowmetry.NPJ cardiovascular health · 2026Article
- AETHER: Video-Based Smartphone Free Flap Monitoring Using Spatial Phase Coherence and Reference-Corrected Augmented Imaging.Computational and structural biotechnology journal · 2026Article
- Machine Learning-Based Identification of Patients with Elevated Central Venous Pressure Using Features Extracted from Photoplethysmography Waveforms.medRxiv : the preprint server for health sciences · 2025Article
- Reliable wrist PPG monitoring by mitigating poor skin sensor contact.Scientific reports · 2025Article
- Wearable technologies for assisted mobility in the real world.Nature communications · 2025Review
- A Multimodal System for Comprehensive Cardiovascular Monitoring Using ECG, PCG, and PPG Signal Fusion.Sensors (Basel, Switzerland) · 2025Article
- Ultrafast fMRI detects age-related changes in harmonics of cardiac pulsations in the brain at 7 T.bioRxiv : the preprint server for biology · 2025Article
- The arterial stiffness and pulse pressure are predictors of intraocular pressure in a middle-aged population.Scientific reports · 2025Article
- Non-Invasive Estimation of Arterial Stiffness Using Photoplethysmography Sensors: An In Vitro Approach.Sensors (Basel, Switzerland) · 2025Article
- Design and validation of a novel multiple sites signal acquisition and analysis system based on pressure stimulation for human cardiovascular information.Scientific reports · 2025Article
- Multi-point sensing organic light-emitting diode display based mobile cardiovascular monitor.Nature communications · 2025Article
- Customisable Silicone Vessels and Tissue Phantoms for In Vitro Photoplethysmography Investigations into Cardiovascular Disease.Sensors (Basel, Switzerland) · 2024Article
- State-dependent facial pulsation asymmetry and phase asynchrony measured by imaging photoplethysmography and their coupling with contingent negative variation in migraine.Frontiers in neurologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular diseases (CVDs) remain the leading cause of global mortality, therefore understanding arterial stiffness is essential to developing innovative technologies to detect, monitor and treat them. The ubiquitous spread of photoplethysmography (PPG), a completely non-invasive blood-volume sensing technology suitable for all ages, highlights immense potential for arterial stiffness assessment in the wider healthcare setting outside specialist clinics, for example during routine visits to a General Practitioner or even at home with the use of mobile and wearable health devices. This study employs a custom-manufactured in vitro cardiovascular system with vessels of varying stiffness to test the hypothesis that PPG signals may be used to detect and assess the level of arterial stiffness under controlled conditions. Analysis of various morphological features demonstrated significant (p < 0.05) correlations with vessel stiffness. Particularly, area related features were closely linked to stiffness in red PPG signals, while for infrared PPG signals the most correlated features were related to pulse-width. This study demonstrates the utility of custom vessels and in vitro investigations to work towards non-invasive cardiovascular assessment using PPG, a valuable tool with applications in clinical healthcare, wearable health devices and beyond.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.