Evidence map›Paper›PMID 38263387›Full record

ArticleScientific reports2024

Verbal fluency patterns associated with the amnestic conversion from mild cognitive impairment to dementia.

Simona Cintoli, Laura Favilli, Riccardo Morganti, Gabriele Siciliano, Roberto Ceravolo, Gloria Tognoni

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simona CintoliDepartment of Medical Specialties - Neurology Unit, AOUP, 56126, Pisa, Italy. s.cintoli@gmail.com.
Laura FavilliDepartment of NEUROFARBA- Section of Psychology, University of Florence, 50135, Florence, Italy.
Riccardo MorgantiDepartment of Clinical and Experimental Medicine, Section of Statistics, University of Pisa, 56126, Pisa, Italy.
Gabriele SicilianoDepartment of Medical Specialties - Neurology Unit, AOUP, 56126, Pisa, Italy.
Roberto CeravoloDepartment of Medical Specialties - Neurology Unit, AOUP, 56126, Pisa, Italy.
Gloria TognoniDepartment of Medical Specialties - Neurology Unit, AOUP, 56126, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with amnestic mild cognitive impairment (aMCI) are at a higher risk of converting to Alzheimer's disease. The aim of this study was to examine the potential use of Verbal Fluency (VF) measures as markers for predicting the conversion to dementia. At baseline, 61 aMCI, aged 65 to 80 years, underwent a comprehensive neuropsychological assessment, including phonemic (PVF) and semantic verbal fluency (SVF) tasks. After 18 months, 14 individuals with aMCI had progressed to a diagnosis of dementia. The findings revealed that aMCI-converter group had lower Mini Mental State Examination and Rey Auditory Verbal Learning Task scores than aMCI-no converter and produced fewer clusters in both VF tasks and a lower number of switches in PVF at baseline (p < 0.05). According to receiver operating characteristic curve analysis, the number of clusters in PVF had the highest predictive value (AUC = 0.80) with a threshold of 5.510 for identifying aMCI-converter at baseline. Additionally, participants with higher levels of education exhibited more clusters and switches in VF tasks (p < 0.05). These results suggest that qualitative measures of VF could serve as neuropsychological markers for predicting cognitive decline in individuals with aMCI. Furthermore, the study highlights the potential influence of the education level on cognitive performance in neuropsychological tasks.

Indexed as

Alzheimer DiseaseCognitive DysfunctionEducational StatusHumansNeuropsychological TestsROC Curve

Identifiers

PMID38263387
PMCPMC10806051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.