Evidence map›Paper›PMID 38263281›Full record

SynthesisProstate cancer and prostatic diseases2025

Single port robot-assisted radical and simple prostatectomy: a systematic review and meta-analysis.

Antonio Franco, Francesco Ditonno, Celeste Manfredi, Antony A Pellegrino, Leslie Claire Licari, Eugenio Bologna, Carol Feng, Alessandro Antonelli, Marco De Sio, Cosimo De Nunzio and 5 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Prostate cancer and prostatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. da VinciBMC surgery · 2026
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  19. Advances in Techniques in Radical Prostatectomy.Medicina (Kaunas, Lithuania) · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Antonio FrancoDepartment of Urology, Rush University, Chicago, IL, USA.
Francesco DitonnoDepartment of Urology, Rush University, Chicago, IL, USA.
Celeste ManfrediDepartment of Urology, Rush University, Chicago, IL, USA.
Antony A PellegrinoDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-0898-1953
Leslie Claire LicariDepartment of Urology, Rush University, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-3274-1247
Eugenio BolognaDepartment of Urology, Rush University, Chicago, IL, USA.
Carol FengDepartment of Urology, Rush University, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-9636-5025
Alessandro AntonelliDepartment of Urology, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-7455-8803
Marco De SioUrology Unit, "Luigi Vanvitelli" University, Naples, Italy.
Cosimo De NunzioDepartment of Urology, Sant'Andrea Hospital, Sapienza University, Rome, Italy.ORCID http://orcid.org/0000-0002-2190-512X
Francesco PorpigliaDepartment of Oncology, Division of Urology, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Italy.
Edward E CherulloDepartment of Urology, Rush University, Chicago, IL, USA.
Jihad KaoukDepartment of Urology, Glickman Institute, Cleveland Clinic, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-7127-6069
Simone CrivellaroDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Riccardo AutorinoDepartment of Urology, Rush University, Chicago, IL, USA. ricautor@gmail.com.ORCID http://orcid.org/0000-0001-7045-7725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAim of our study was to review the current evidence on single port robot-assisted radical prostatectomy (SP-RARP) and SP robot-assisted simple prostatectomy (SP-RASP) procedures.

methodsA comprehensive bibliographic search on multiple databases was conducted in July 2023. Studies were included if they assessed patients with non-metastatic prostate cancer or candidate for benign prostatic hyperplasia surgery (P) who underwent SP-RARP or SP-RASP, respectively, (I), compared or not with other surgical techniques (C), evaluating perioperative, oncological, or functional outcomes (O). Prospective and retrospective original articles were included (S). A meta-analysis of comparative studies between SP-RARP and MP-RARP was performed.

resultsA total of 21 studies investigating 1400 patients were included in our systematic review, 18 were related to SP-RARP while 3 to SP-RASP. Only 8 comparative studies were eligible for meta-analysis. Mean follow-up was 8.1 (±5.8) months. Similar outcomes were observed for SP-RARP and MP-RARP in terms of operative time, catheterization time, pain score, complications rate, continence and potency rates, positive surgical margin, and biochemical recurrence. Length of hospital stay was shorter in the SP group after sensitivity analysis (WMD -0.58, 95% IC -1.17 to -0.9, p < 0.05). Subgroup analysis by extraperitoneal approach did not show any statistical difference, except for a lower positive margins rate in the SP extraperitoneal technique compared to MP-RARP. Overall, SP-RASP exhibited shorter hospital stay and lower rate of de novo urinary incontinence when compared to other techniques, while no differences were reported in terms of postoperative International Prostate Symptom Score, post void residual and maximum flow.

conclusionsOverall comparable oncological, functional, and perioperative outcomes can be achieved with SP platform. Subgroup analysis by different approaches did not reveal significant variations in outcomes. However, the retrospective nature of the studies, the limited follow-up, and the relatively small sample size of selected Centers may impact these results.

Indexed as

ProstatectomyProstatic HyperplasiaProstatic NeoplasmsRobotic Surgical ProceduresHumansMalePostoperative ComplicationsTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.