ArticleJournal of translational medicine2024
Association between the systemic immune inflammation index and periodontitis: a cross-sectional study.
Article in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Impact of periodontal microRNAs associated with alveolar bone remodeling during orthodontic tooth movement: a randomized clinical trial.Journal of translational medicine · 2024Trial
- Serum IL-6 and IL-10 in Early Childhood Caries: A Sibling-Controlled Study in Children Aged 2.5-6 Years.Diagnostics (Basel, Switzerland) · 2026Article
- Periodontitis as a potential predisposing factor for gallstone cholecystitis: exploring the role of chronic systemic inflammation.Surgery today · 2026Observational
- Article
- Unveiling the link between oral microbial α-diversity, advanced cardiovascular-kidney-metabolic syndrome, and mortality.Journal of oral microbiology · 2026Article
- Associations of systemic inflammation response index and systemic immune-inflammation index with proxy-assessed sarcopenia in community-dwelling older adults.Frontiers in medicine · 2026Article
- Effect of age and systemic inflammation on the association between severity of periodontitis and blood pressure in periodontitis patients.BMC oral health · 2025Article
- Mediating role of systemic immune-inflammation index between heavy metal exposure and hepatic steatosis/hepatic fibrosis: evidence from NHANES 2005-2020.Frontiers in nutrition · 2025Article
- A study on the correlation of thyroid nodules with METS-IR and SII in a population undergoing health checkups.Frontiers in endocrinology · 2025Article
- The Association Between Periodontitis and the Prevalence and Prognosis of Metabolic Syndrome.Journal of multidisciplinary healthcare · 2025Article
- Association between cardiometabolic index (CMI) and periodontitis in US adults: analysis of NHANES data (2009-2014).BMC oral health · 2024Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundPeriodontitis is a chronic oral inflammatory disease that seriously affects people's quality of life. The purpose of our study was to investigate the correlation between the systemic immune inflammation index (SII) and periodontitis by utilizing a large national survey. This will establish a reference for the early identification and management of periodontitis.
methodsThis study comprised the adult US population who participated in a national periodontitis surveillance project during the six years from 2009 to 2014. Through the utilization of univariate and multivariate weighted logistic regression, we investigated the correlation between the systemic immune inflammation index and periodontitis. Additionally, we employed sensitivity analyses to evaluate the robustness of our findings.
resultsThe study involved 10,366 participants with an average age of 51.00 years, of whom 49.45% were male (N = 5126) and 50.55% were female (N = 5240). The prevalence of periodontitis is estimated to be about 38.43% in the US adults aged 30 or older population. Our logistic regression models indicated a positive association between a SII higher than 978 × 10
conclusionsOur study highlights that SII is associated with periodontitis in a nationally representative sample of US adults. And the SII is significantly associated with a high risk of periodontitis in individuals aged 50 or older.
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