SynthesisBMC cardiovascular disorders2024
Transcatheter aortic valve implantation versus surgical aortic valve replacement for pure aortic regurgitation: a systematic review and meta-analysis of 33,484 patients.
Synthesis in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Contemporary Overview of Aortic Regurgitation in Young Individuals: Insights From Real-Life Evidence.Journal of the American Heart Association · 2026Review
- Comparing TA-TAVR and SAVR in severe aortic regurgitation: outcomes and valve haemodynamics.Open heart · 2026Article
- Asymptomatic Aortic Regurgitation: Evolving Imaging Markers and Contemporary Intervention Strategies.Journal of clinical medicine · 2026Review
- Five-Year Survival After Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Severe Aortic Valve Stenosis-Do We Choose the Right Treatment for Each Patient? A Propensity Score Matched Analysis.Journal of personalized medicine · 2025Article
- Cardiogenic shock in a patient with combined severe aortic and mitral regurgitation treated by a totally percutaneous approach: a case report.European heart journal. Case reports · 2025Article
- What Are SAVR Indications in the TAVI Era?Journal of clinical medicine · 2025Review
- Transcatheter treatment of pure aortic regurgitation.Nature reviews. Cardiology · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe published studies comparing transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) in pure aortic regurgitation (AR) are conflicting. We conducted this systematic review and meta-analysis to compare TAVI with SAVR in pure AR.
methodsWe searched PubMed, Embase, Web of Science (WOS), Scopus, and the Cochrane Library Central Register of Controlled Trials (CENTRAL) from inception until 23 June 2023. Review Manager was used for statistical analysis. The risk ratio (RR) with a 95% confidence interval (CI) was used to compare dichotomous outcomes. Continuous outcomes were compared using the mean difference (MD) and 95% CI. The inconsistency test (I
resultsWe included six studies with 5633 patients in the TAVI group and 27,851 in SAVR. In-hospital mortality was comparable between TAVI and SAVR (RR = 0.89, 95% CI [0.56, 1.42], P = 0.63) (I
conclusionTAVI reduces in-hospital stroke and is associated with better safety outcomes than SAVR in patients with pure AR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.