Evidence map›Paper›PMID 38262725›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in Mice.

Josue A Lopez, Luis O Romero, Wai-Lin Kaung, J Wesley Maddox, Valeria Vásquez, Amy Lee

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. A Tac1-Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Josue A LopezDepartment of Neuroscience and Center for Learning and Memory, University of Texas-Austin, Austin 78712, Texas.ORCID 0000-0003-0232-4407
Luis O RomeroDepartment of Physiology, The University of Tennessee Health Science Center, Memphis 38163, Tennessee.ORCID 0000-0001-9855-7592
Wai-Lin KaungDepartment of Neuroscience and Center for Learning and Memory, University of Texas-Austin, Austin 78712, Texas.ORCID 0009-0001-3286-6349
J Wesley MaddoxDepartment of Neuroscience and Center for Learning and Memory, University of Texas-Austin, Austin 78712, Texas.
Valeria VásquezDepartment of Physiology, The University of Tennessee Health Science Center, Memphis 38163, Tennessee.
Amy LeeDepartment of Neuroscience and Center for Learning and Memory, University of Texas-Austin, Austin 78712, Texas amy.lee1@austin.utexas.edu.ORCID 0000-0001-8021-0443
The University of Texas at Austin · USUniversity of Tennessee Health Science Center · US

Funding

Calcium channels in retinal photoreceptorsR01EY026817 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI LEE, AMY · 2017 to 2025
$4.4M
Interdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7M
Training in Learning and MemoryT32MH106454 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI PRESTON, ALISON R · 2015 to 2025
$2.1M
Regulation of mechanosensitive ion channels by membrane lipidsR01GM133845 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI VASQUEZ, VALERIA · 2019 to 2023
$1.9M
NIGMS NIH HHS R01 GM133845NINDS NIH HHS T32 NS045549
6 · The paper itself

Abstract

The sense of touch is crucial for cognitive, emotional, and social development and relies on mechanically activated (MA) ion channels that transduce force into an electrical signal. Despite advances in the molecular characterization of these channels, the physiological factors that control their activity are poorly understood. Here, we used behavioral assays, electrophysiological recordings, and various mouse strains (males and females analyzed separately) to investigate the role of the calmodulin-like Ca

Indexed as

Ion ChannelsTouchAnimalsCalcium-Binding ProteinsFemaleMaleMechanotransduction, CellularMiceNeuronsCa2+-binding protein-1Calcium-Binding ProteinsIon ChannelsPiezo2 protein, mousecalciumdorsal root ganglionion channelmechanosensationPIEZO2touch sensation

Identifiers

PMID38262725
PMCPMC10919251
OpenAlexW4391131182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.