ReviewOpen biology2024
Plant NLR immunity activation and execution: a biochemical perspective.
Review in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
27 citing papers in PubMed, 46 citations in OpenAlex.
- An atypical EF-hand domain containing resistance protein SRC4 boosts plant immunity in a calcium-enhanced manner.The Plant journal : for cell and molecular biology · 2026Article
- Pioneering plant virology research for a healthier future: a summary of the 2025 American Society for Virology (ASV) Plant Virology Satellite Symposium.Journal of virology · 2026Article
- Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance.The plant genome · 2026Review
- Single-Cell Transcriptomics Reveals FLS2-Dependent Hypoxia Signaling and ERF13-Mediated Transcription During flg22-Triggered Immunity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A fellowship of the rings in plant defence.Nature · 2026Article
- Plant immune inducers from fundamental research to applications: Past achievements, current challenges, and future perspectives.Plant communications · 2026Review
- NLRSeek: A reannotation-based pipeline for mining missing NLR genes in sequenced genomes.aBIOTECH · 2026Article
- Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- HIPPs of all trades: insights from pathogens on the function of HMA proteins at plasmodesmata.Journal of experimental botany · 2026Review
- TIR innovations in plant immunity.The New phytologist · 2026Review
- Dissection of the Ren6 and Ren7 powdery mildew resistance loci in Vitis piasezkii DVIT2027 using phased parental-progeny genomes and intraspecific locus graph reconstruction.G3 (Bethesda, Md.) · 2025Article
- Disruption of the mRNA m6A writer complex triggers autoimmunity in Arabidopsis.PLoS genetics · 2025Article
- Genome-Wide Identification and Functional Evolution of NLR Gene Family inCurrent issues in molecular biology · 2025Article
- Metabolic hubs under attack: Effector-mediated manipulation of plant inositol phosphate signaling.PLoS pathogens · 2025Article
- Coordinated actions of NLR-assembled and glutamate receptor-like calcium channels in plant effector-triggered immunity.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Integrated transcriptome and BSA-seq analysis identifies a novel QTL for Meloidogyne graminicola resistance in rice HuaHang31.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Regeneration and defense: unveiling the molecular interplay in plants.The New phytologist · 2025Review
- In silico prediction method for plant Nucleotide-binding leucine-rich repeat- and pathogen effector interactions.The Plant journal : for cell and molecular biology · 2025Article
- Article
- Atypical RXLR effectors are involved inaBIOTECH · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants deploy cell-surface and intracellular receptors to detect pathogen attack and trigger innate immune responses. Inside host cells, families of nucleotide-binding/leucine-rich repeat (NLR) proteins serve as pathogen sensors or downstream mediators of immune defence outputs and cell death, which prevent disease. Established genetic underpinnings of NLR-mediated immunity revealed various strategies plants adopt to combat rapidly evolving microbial pathogens. The molecular mechanisms of NLR activation and signal transmission to components controlling immunity execution were less clear. Here, we review recent protein structural and biochemical insights to plant NLR sensor and signalling functions. When put together, the data show how different NLR families, whether sensors or signal transducers, converge on nucleotide-based second messengers and cellular calcium to confer immunity. Although pathogen-activated NLRs in plants engage plant-specific machineries to promote defence, comparisons with mammalian NLR immune receptor counterparts highlight some shared working principles for NLR immunity across kingdoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.