Evidence map›Paper›PMID 38262413›Full record

ReviewNeuron2024

Neuronal ensembles: Building blocks of neural circuits.

Rafael Yuste, Rosa Cossart, Emre Yaksi

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuron, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
35.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 105 citations in OpenAlex.

  1. Trial
  2. Article
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  5. Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. Stable neuronal representations underlie cognitive resilience to Alzheimer's disease pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Contamination of Engram Coactivity Networks During Forgetting.bioRxiv : the preprint server for biology · 2026
    Article
  17. Article
  18. Live Spike Sorting of Large-scale Neural Recordings.bioRxiv : the preprint server for biology · 2026
    Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 4 countries.

Rafael YusteNeuroTechnology Center, Department of Biological Sciences, Columbia University, New York, NY, USA. Electronic address: rmy5@columbia.edu.
Rosa CossartInserm, INMED, Turing Center for Living Systems Aix-Marseille University, Marseille, France. Electronic address: rosa.cossart@inserm.fr.
Emre YaksiKavli Institute for Systems Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway; Koç University Research Center for Translational Medicine, Koç University School of Medicine, Istanbul, Turkey. Electronic address: emre.yaksi@ntnu.no.
Columbia University · USInserm · FRKoç University · TR

Funding

Reexamining the Role of Dendrites in Neuronal FunctionRM1NS132981 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Jayeeta Basu, RAFAEL YUSTE · 2023 to 2026
$10.3M
Effect of GABAergic inhibition of dendritic spines on synaptic pruning in the medial prefrontal cortex during adolescenceR01MH115900 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2019 to 2023
$3.2M
Mechanisms of Neuronal Ensembles in Visual CortexR01EY035248 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI RAFAEL YUSTE · 2024 to 2026
$1.7M
NEI NIH HHS R01 EY035248NIMH NIH HHS R01 MH115900NINDS NIH HHS RM1 NS132981
6 · The paper itself

Abstract

Neuronal ensembles, defined as groups of neurons displaying recurring patterns of coordinated activity, represent an intermediate functional level between individual neurons and brain areas. Novel methods to measure and optically manipulate the activity of neuronal populations have provided evidence of ensembles in the neocortex and hippocampus. Ensembles can be activated intrinsically or in response to sensory stimuli and play a causal role in perception and behavior. Here we review ensemble phenomenology, developmental origin, biophysical and synaptic mechanisms, and potential functional roles across different brain areas and species, including humans. As modular units of neural circuits, ensembles could provide a mechanistic underpinning of fundamental brain processes, including neural coding, motor planning, decision-making, learning, and adaptability.

Indexed as

BrainNeuronsHumansLearningassemblyattractorneural networkssynfire

Identifiers

PMID38262413
PMCPMC10957317
OpenAlexW4391101094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.