Evidence map›Paper›PMID 38261812›Full record

ArticleActa pharmaceutica Sinica. B2024

Mitochondria-specific near-infrared photoactivation of peroxynitrite upconversion luminescent nanogenerator for precision cancer gas therapy.

Hui Yu, Aliya Tiemuer, Xufeng Yao, Mingyuan Zuo, Hai-Yan Wang, Yi Liu, Xiaoyuan Chen

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui YuDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 211198, China.
Aliya TiemuerDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 211198, China.
Xufeng YaoDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 211198, China.
Mingyuan ZuoDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 211198, China.
Hai-Yan WangSchool of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Yi LiuDepartment of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 211198, China.
Xiaoyuan ChenDepartments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore 119074, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gas therapy is emerging as a highly promising therapeutic strategy for cancer treatment. However, there are limitations, including the lack of targeted subcellular organelle accuracy and spatiotemporal release precision, associated with gas therapy. In this study, we developed a series of photoactivatable nitric oxide (NO) donors NRh-R-NO (R = Me, Et, Bn,

Indexed as

Gas therapyIn vivoMitochondrionNanogeneratorNear infraredPeroxynitritePhoto-triggeredUpconversion luminescent bioimaging

Identifiers

PMID38261812
PMCPMC10792980

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.