Evidence map›Paper›PMID 38261079›Full record

ArticleOral and maxillofacial surgery2024

Percutaneous injection of sclerosant agents as an effective treatment for cystic malformations of the head and neck.

Ilaria Paladini, Silvia Schirò, Roberta Eufrasia Ledda, Ludovica Leo, Gianluca Milanese, Enrico Epifani, Andrea Andreone, Giulia Capurri, Matteo Fantoni, Andrea Gemignani and 3 more

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Article in Oral and maxillofacial surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Ilaria PaladiniUnit of Interventional Radiology, Diagnostic Department, Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Silvia SchiròDepartment of Medicine and Surgery (DiMec), University of Parma, Via gramsci 14 (43126), Parma, Italy. silvia.schiro@unipr.it.
Roberta Eufrasia LeddaDepartment of Medicine and Surgery (DiMec), University of Parma, Via gramsci 14 (43126), Parma, Italy.
Ludovica LeoDepartment of Medicine and Surgery (DiMec), University of Parma, Via gramsci 14 (43126), Parma, Italy.
Gianluca MilaneseUnit of "Scienze Radiologiche", Department of Medicine and Surgery (DiMeC), University Hospital of Parma, Parma, Italy.
Enrico EpifaniUnit of Interventional Radiology, Diagnostic Department, Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Andrea AndreoneUnit of Interventional Radiology, Diagnostic Department, Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Giulia CapurriUnit of Interventional Radiology, Diagnostic Department, Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
Matteo FantoniNeuroradiology Unit, Diagnostic Department, University Hospital of Parma, Via Volturno 39, 43125, Parma, Italy.
Andrea GemignaniDepartment of Medicine and Surgery (DiMec), University of Parma, Via gramsci 14 (43126), Parma, Italy.
Alessandro GrittiMaxillo-Facial Surgery Division, Head and Neck Department, University Hospital of Parma,, Parma, Italy.
Enrico SesennaMaxillo-Facial Surgery Division, Head and Neck Department, University Hospital of Parma, Parma, Italy.
Roberto MenozziInterventional Neuroradiology Unit, Diagnostic Department, University Hospital of Parma, Via Volturno 39, 43125, Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the clinical and aesthetic outcome of percutaneous injection of sclerosant agents to treat head and neck cystic malformations (HNCM) and to assess their recurrence rate based on histology and site.

methodsFifty-four subjects (mean age 46 years) with HNCM treated by percutaneous injection of sclerosant agents between January and December 2017 were included. Imaging and clinical data before and after the procedure were collected. Quality of Life Index, Pain Visual Analogue Scale, and Aesthetic Scale scores were measured to assess clinical and aesthetic outcomes. A size reduction of ≥ 70% assessed through the visual scale was considered significant.

resultsOf the 54 HNCM, there were 26 (48%) lymphatic malformations (LM), 13 (24%) salivary epithelial duct cysts of the parotid gland, 12 (22%) salivary mucoceles, and 3 (5%) branchial cysts. A significant size reduction and a satisfactory clinical-aesthetic outcome were observed in all types of LM. The number of reinterventions was significantly associated with the number of lesions (p < 0.001). The lowest number of interventions was observed in macrocystic lymphatic malformations (average of 1.2 interventions). All salivary epithelial duct cysts showed a significant reduction in size, a satisfactory clinical-aesthetic outcome, and an average of 1.16 interventions per patient. Mucoceles had a worse response, with only 3/14 patients showing a satisfactory and long-lasting clinical outcome (average of 1.16 interventions). Treatment of branchial cysts showed the worst outcome with a limited clinical response (3/3).

conclusionPercutaneous injection of sclerosant agents may be considered as a first-line treatment for LM and salivary epithelial duct cysts.

Indexed as

CystsLymphatic AbnormalitiesSclerosing SolutionsAdolescentAdultAgedBranchiomaChildChild, PreschoolEstheticsFemaleHumansMaleMiddle AgedMucoceleSclerotherapySclerosing SolutionsHead and neck cystic malformationInterventional radiologyPercutaneous sclerotherapy

Identifiers

PMID38261079
OpenAlexW4391142547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.