SynthesisDer Nervenarzt2024
[Efficacy of internet-based interventions for depression available in Germany-A systematic review and meta-analysis].
Synthesis in Der Nervenarzt, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Efficacy of prescription-eligible digital health applications for depression and generalized anxiety disorder in Germany: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- What internet- and mobile-based interventions are currently available for adults with overweight or obesity experiencing symptoms of depression? A systematic review.International journal of obesity (2005) · 2025Pooled it
- Digital therapeutics for depression in Germany: A systematic app review.Internet interventions · 2026Article
- Clinical utility of digital technologies in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Perspectives on digital therapeutic prescribing: a qualitative study among German psychological psychotherapists.Frontiers in digital health · 2026Article
- Article
- [Digital health applications for depressive disorders in Germany : A narrative review of the evidence and integration into treatment].Der Nervenarzt · 2025Review
- Digital Health Applications (DiGA) for Treating Depression and Generalized Anxiety Disorder: Protocol for a Systematic Health App Review and Systematic Review of Published Evidence.JMIR research protocols · 2025Article
- The Use of Mobile Apps in Adolescent Psychotherapy: Assessment of Psychotherapists' Perspectives.JMIR formative research · 2025Article
- Current trends in e-mental health interventions: Health care providers' attitudes and usage patterns.Internet interventions · 2025Article
- [How to overcome barriers to care with digital health applications (DiGA)? A review of the patient pathway for unipolar depression].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Review
- Why do psychotherapists use so little e-mental health in psychotherapy? Insights from a sample of psychotherapists in Germany.PLOS mental health · 2025Article
- [Digital health applications-What we should know as rheumatologists].Zeitschrift fur Rheumatologie · 2024Review
- Cost-effectiveness analysis of mHealth applications for depression in Germany using a Markov cohort simulation.NPJ digital medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInternet-based interventions (IBIs) for the treatment of depression have been found to have positive effects in international meta-analyses; however, it is unclear whether these effects also extend to IBIs specifically available in Germany. The aim of this meta-analysis was to estimate the immediate effects and the long-term effects of IBIs available in Germany free of charge or available on prescription and covered by the public health insurances as so-called digital health applications (DiGAs) and to compare the efficacy of DiGAs and freely available IBIs.
methodA systematic literature search and random-effects meta-analysis were performed (preregistration: INPLASY202250070). Randomized controlled trials (RCTs) of IBIs freely available in Germany or as DiGA in adults with elevated depressive symptoms were compared with active and inactive controls available at the time of the survey in May 2022.
resultsA total of six interventions were identified: COGITO, deprexis, iFightDepression, moodgym, Novego, and Selfapy. The pooled effect size of a total of 28 studies with 13,413 participants corresponded to an effect of Cohen's d = 0.42, (95% confidence interval, CI: 0.31-0.54, I
conclusionThe IBIs for depressive disorders available in Germany are effective and can therefore be used in the treatment of people with a depressive disorder; however, it is possible that not all interventions are equally effective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.