Evidence map›Paper›PMID 38260890›Full record

ArticleFrontiers in microbiology2023

Evaluation of proline-rich antimicrobial peptides as potential lead structures for novel antimycotics against

Alexandra Brakel, Thomas Grochow, Stefanie Fritsche, Daniel Knappe, Andor Krizsan, Simone A Fietz, Gottfried Alber, Ralf Hoffmann, Uwe Müller

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Artificial intelligence catalyzes antimicrobial peptide design.Synthetic and systems biotechnology · 2027
    Review
  2. Review
  3. Article
  4. Proline-Rich Antimicrobial Peptides from Invertebrates.Molecules (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Article
  7. Blap-6, a Novel Antifungal Peptide from the Chinese Medicinal BeetleInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alexandra BrakelInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Bioanalytical Chemistry, Leipzig University, Leipzig, Germany.
Thomas GrochowInstitute of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Stefanie FritscheCenter for Biotechnology and Biomedicine, Leipzig University, Leipzig, Germany.
Daniel KnappeInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Bioanalytical Chemistry, Leipzig University, Leipzig, Germany.
Andor KrizsanInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Bioanalytical Chemistry, Leipzig University, Leipzig, Germany.
Simone A FietzInstitute of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Gottfried AlberCenter for Biotechnology and Biomedicine, Leipzig University, Leipzig, Germany.
Ralf HoffmannInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Bioanalytical Chemistry, Leipzig University, Leipzig, Germany.
Uwe MüllerCenter for Biotechnology and Biomedicine, Leipzig University, Leipzig, Germany.
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cryptococcosis and cryptococcal meningitis, caused by Results: A preliminary screening of the minimal inhibitory concentrations (MICs) of 20 AMPs, including the well-known PrAMPs Onc112, Api137, and Chex1Arg20 as well as the cathelicidin CRAMP against the

Indexed as

antifungal peptidefungal pathogenintracellular mode-of-actionproline-rich antimicrobial peptide (PrAMP)scanning electron microscopy

Identifiers

PMID38260890
PMCPMC10800876
OpenAlexW4390667040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.