SynthesisFrontiers in psychiatry2023
Prevalence of depression in melasma: a systematic review and meta-analysis.
Synthesis in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- Safety and efficacy of niosomal and conventional tranexamic acid/niacinamide vs. hydroquinone creams in melasma: A randomized, double-blind, case-controlled clinical trial.Scientific reports · 2025Trial
- Amber LED photobiomodulation versus tranexamic acid for the treatment of melasma: randomized controlled double-blind pilot trial.Lasers in medical science · 2025Trial
- Innovations in Refractory Melasma: Mechanism-Based Management and Emerging Therapeutic Strategies.Cureus · 2026Review
- Article
- Exploring the Effectiveness, Tolerability, and Safety of the Adjunctive Use of Microneedling With Tranexamic Acid in the Treatment of Melasma.Journal of cosmetic dermatology · 2026Review
- Biocosmetic Potential of Xylaria psidii, an Endophyte of Aegle marmelos.Current microbiology · 2026Article
- Identification of Hub genes in melasma using integrated transcriptomic analysis.Bioinformation · 2026Article
- A Retrospective Analysis of Radiofrequency Microneedling for Melasma Management in the Japanese Population.Clinical, cosmetic and investigational dermatology · 2026Article
- Nerve Block-Assisted Intradermal Injection of Tranexamic Acid, Vitamin C, and Glutathione for Melasma: A Split-Face Comparative Study.Aesthetic plastic surgery · 2025Article
- Psychosocial impact of melasma: Asian Americansand people with pre-existing mood or anxiety disorders are disproportionately affected.Research square · 2025Article
- Melasma secondary to drugs: a real-world pharmacovigilance study of the FDA adverse event reporting system (FAERS).BMC pharmacology & toxicology · 2025Article
- Latin American consensus on the treatment of melasma.International journal of dermatology · 2025Review
- Prevalence and associated factors of depression and anxiety among patients with melasma: a cross-sectional study in China.Frontiers in psychiatry · 2025Article
- Exploring Melasma Patients' Needs Through Social Media: A Qualitative Study.Patient preference and adherence · 2025Article
- Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation.Clinical, cosmetic and investigational dermatology · 2024Article
- Depressive and anxious symptoms in melasma during pregnancy: a cross-sectional study.Anais brasileiros de dermatologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Due to cosmetic disfigurement, melasma can negatively affect the quality of life and emotional and mental health, further leading to depression. Objective: Prevalence rates of depression in patients with melasma vary widely across studies. The aim of this systematic review and meta-analysis was to estimate the prevalence of depression among melasma patients. Methods: The PubMed, Embase, Web of Science, and Scopus databases were searched to identify articles evaluating the prevalence of depression in melasma patients from their inception to 12 July 2023. Studies were reviewed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and a meta-analysis was performed using the Stata 14.0 software. Results: Sixteen studies met the eligibility criteria out of the 859 studies, containing a total of 2,963 melasma patients for this systematic review and meta-analysis. Meta-analyses revealed that the pooled prevalence of depression among patients with melasma was 43.4% (95% CI 30.5-56.2%, Conclusion: The prevalence of depression was relatively high in patients with melasma, and there was a correlation between melasma and depression, encouraging clinicians to screen for depression in their patients and providing a combination of physical and psychosocial support. If necessary, they should be referred to formal mental health services to seek professional psychological intervention. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, CRD42022381378.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.