Evidence map›Paper›PMID 38260724›Full record

Trial reportInfluenza and other respiratory viruses2024

Comparison of influenza viral load in nasopharyngeal and midturbinate swabs.

Corrado Bernasconi, Laurie Katugampola, Steffen Wildum

Abstract readRandomized Controlled TrialClinical Trial, Phase III
In one paragraph

Trial report in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Influenza.Nature reviews. Disease primers · 2026
    Review
  3. Saliva and Anterior Nasal Samples for Detecting Respiratory Viruses in Children.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Corrado BernasconiF. Hoffmann-La Roche Ltd. Basel Switzerland.ORCID 0000-0002-1019-5468
Laurie KatugampolaRoche Products Ltd. Welwyn Garden City UK.
Steffen WildumF. Hoffmann-La Roche Ltd. Basel Switzerland.ORCID 0000-0001-9779-5740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different specimen types are used for influenza diagnosis but comparative data for viral loads from different swab types are limited. We compared influenza viral loads (determined by quantitative reverse transcription polymerase chain reaction [RT-PCR]) in 93 paired midturbinate and nasopharyngeal swab aliquots from influenza infected patients enrolled in a phase 3 randomized-controlled study with the objective of maximizing the number of swabs available for sequence analysis. Midturbinate swabs yielded a 53% lower viral load versus nasopharyngeal swabs, and this difference was similar for influenza A and B. These data suggest that nasopharyngeal swabs might be preferred in diagnostic settings when obtaining higher viral load is important.

Indexed as

Influenza, HumanHumansNasopharynxSerologic TestsViral LoadCENTERSTONEinfluenza virusmidturbinate swabnasopharyngeal swabspecimen typeviral load

Identifiers

PMID38260724
PMCPMC10800293

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.