Evidence map›Paper›PMID 38260687›Full record

ArticlebioRxiv : the preprint server for biology2024

ER-detect: a pipeline for robust detection of early evoked responses in BIDS-iEEG electrical stimulation data.

Max A van den Boom, Nicholas M Gregg, Gabriela Ojeda Valencia, Brian N Lundstrom, Kai J Miller, Dorien van Blooijs, Geertjan J M Huiskamp, Frans S S Leijten, Gregory A Worrell, Dora Hermes

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Max A van den BoomDepartment of Physiology and Biomedical Engineering, Mayo Clinic; Rochester, MN, USA.ORCID 0000-0001-5481-1659
Nicholas M GreggDepartment of Neurology, Mayo Clinic, Rochester, MN; USA.ORCID 0000-0002-6151-043X
Gabriela Ojeda ValenciaDepartment of Physiology and Biomedical Engineering, Mayo Clinic; Rochester, MN, USA.ORCID 0000-0002-5002-3310
Brian N LundstromDepartment of Neurology, Mayo Clinic, Rochester, MN; USA.ORCID 0000-0002-5310-5549
Kai J MillerDepartment of Neurosurgery, Mayo Clinic; Rochester, MN, USA.ORCID 0000-0002-6687-6422
Dorien van BlooijsDepartment of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht; Utrecht, NL.ORCID 0000-0002-7998-414X
Geertjan J M HuiskampDepartment of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht; Utrecht, NL.ORCID 0000-0001-6397-5559
Frans S S LeijtenDepartment of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht; Utrecht, NL.ORCID 0000-0003-2603-3364
Gregory A WorrellDepartment of Physiology and Biomedical Engineering, Mayo Clinic; Rochester, MN, USA.ORCID 0000-0003-2916-0553
Dora HermesDepartment of Physiology and Biomedical Engineering, Mayo Clinic; Rochester, MN, USA.ORCID 0000-0002-8683-8909

Funding

Neurophysiologically Based Brain State Tracking & Modulation in Focal EpilepsyUH2NS095495 · NINDS · MAYO CLINIC ROCHESTER · PI WORRELL, GREGORY A · 2015 to 2018
$4.2M
Neurophysiologically Based Brain State Tracking & Modulation in Focal EpilepsyUH3NS095495 · NINDS · MAYO CLINIC ROCHESTER · PI WORRELL, GREGORY A · 2019 to 2021
$2.8M
CRCNS: Processing speed in the human connectome across the lifespanR01MH122258 · NIMH · MAYO CLINIC ROCHESTER · PI HERMES, DORA · 2019 to 2023
$1.8M
NIMH NIH HHS R01 MH122258NINDS NIH HHS UH2 NS095495NINDS NIH HHS UH3 NS095495
6 · The paper itself

Abstract

Human brain connectivity can be measured in different ways. Intracranial EEG (iEEG) measurements during single pulse electrical stimulation provide a unique way to assess the spread of electrical information with millisecond precision. To provide a robust workflow to process these cortico-cortical evoked potential (CCEP) data and detect early evoked responses in a fully automated and reproducible fashion, we developed Early Response (ER)-detect. ER-detect is an open-source Python package and Docker application to preprocess BIDS structured iEEG data and detect early evoked CCEP responses. ER-detect can use three response detection methods, which were validated against 14-manually annotated CCEP datasets from two different sites by four independent raters. Results showed that ER-detect's automated detection performed on par with the inter-rater reliability (Cohen's Kappa of

Identifiers

PMID38260687
PMCPMC10802406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.