Evidence map›Paper›PMID 38260641›Full record

ArticleResearch square2024

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.

Yang Yu, Xin Wang, Jordan Fox, Ruofan Yu, Pilendra Thakre, Brenna McCauley, Nicolas Nikoloutsos, Qian Li, P J Hastings, Weiwei Dang and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yang YuBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
Xin WangDepartment of Cardiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Jordan FoxBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
Ruofan YuBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
Pilendra ThakreBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
Brenna McCauleyHuffington Center on Aging, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Nicolas NikoloutsosHuffington Center on Aging, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.ORCID 0000-0002-5324-7109
Qian LiBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
P J HastingsBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
Weiwei DangBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.ORCID 0000-0002-6931-4636
Kaifu ChenDepartment of Cardiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.ORCID 0000-0003-1009-4357
Grzegorz IraBaylor College of Medicine, Department of Molecular and Human Genetics, One Baylor Plaza, Houston, TX 77030, USA.
Baylor College of Medicine · USBoston Children's Hospital · US

Funding

Regulation of DNA recombination in Saccharomyces cerevisiaeR01GM080600 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI IRA, GRZEGORZ A · 2007 to 2024
$5.5M
Regulation of Initial Steps of Chromosomal Breaks RepairR01GM125650 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI IRA, GRZEGORZ A · 2018 to 2025
$2.9M
Regulation of longevity through maintenance of transcription fidelityR01AG052507 · NIA · BAYLOR COLLEGE OF MEDICINE · PI DANG, WEIWEI · 2017 to 2021
$2.2M
Bioinformatics Techniques to Analyze Dynamic Changes of 3D GenomeR01GM138407 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI CHEN, KAIFU · 2022 to 2025
$1.8M
Molecular mechanisms of cellular response to age-associated chromatin changesR01AG081347 · NIA · BAYLOR COLLEGE OF MEDICINE · PI Weiwei Dang · 2023 to 2026
$1.4M
NIA NIH HHS R01 AG052507NIA NIH HHS R01 AG081347NIGMS NIH HHS R01 GM080600NIGMS NIH HHS R01 GM125650NIGMS NIH HHS R01 GM138407
6 · The paper itself

Abstract

In metazoans release of mitochondrial DNA or retrotransposon cDNA to cytoplasm can cause sterile inflammation and disease

Identifiers

PMID38260641
PMCPMC10802722
OpenAlexW4390606287

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.