Evidence map›Paper›PMID 38260630›Full record

ArticlebioRxiv : the preprint server for biology2024

An internally controlled system to study microtubule network diversification links tubulin evolution to the use of distinct microtubule regulators.

Andrew S Kennard, Katrina B Velle, Ravi Ranjan, Danae Schulz, Lillian K Fritz-Laylin

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrew S KennardDepartment of Biology, University of Massachusetts, Amherst MA, United States.ORCID 0000-0002-0472-9144
Katrina B VelleDepartment of Biology, University of Massachusetts, Amherst MA, United States.ORCID 0000-0002-9985-9522
Ravi RanjanGenomics Resource Laboratory, Institute of Applied Life Sciences, University of Massachusetts, Amherst MA, United States.ORCID 0000-0002-8768-549X
Danae SchulzDepartment of Biology, Harvey Mudd College, Claremont CA, United States.ORCID 0000-0002-0392-7245
Lillian K Fritz-LaylinDepartment of Biology, University of Massachusetts, Amherst MA, United States.ORCID 0000-0002-9237-9403
University of Massachusetts Amherst · USHarvey Mudd College · US

Funding

Chytrid fungi and the functional specification of actin networksR35GM143039 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI FRITZ-LAYLIN, LILLIAN KATHLEEN · 2021 to 2025
$1.9M
Defining cytoskeletal mechanisms driving cell motility in NaegleriaK99GM147656 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI VELLE, KATRINA · 2022 to 2023
$146k
Defining mechanisms of mitotic spindle organization in NaegleriaF32GM148023 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI KENNARD, ANDREW STEVEN · 2022 to 2024
$141k
NIGMS NIH HHS F32 GM148023NIGMS NIH HHS K99 GM147656NIGMS NIH HHS R35 GM143039
6 · The paper itself

Abstract

Diverse eukaryotic cells assemble microtubule networks that vary in structure and composition. While we understand how cells build microtubule networks with specialized functions, we do not know how microtubule networks diversify across deep evolutionary timescales. This problem has remained unresolved because most organisms use shared pools of tubulins for multiple networks, making it impossible to trace the evolution of any single network. In contrast, the amoeboflagellate

Identifiers

PMID38260630
PMCPMC10802493
OpenAlexW4390700273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.