In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 5 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
13 authors at 2 institutions in 1 country.
Nicole ThompsonEIT and Neurophysiology Research Group, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.ORCID 0000-0002-4153-9614 Enrico RavagliEIT and Neurophysiology Research Group, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.ORCID 0000-0002-4874-9366 Svetlana MastitskayaEIT and Neurophysiology Research Group, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.ORCID 0000-0002-4819-2908 Ronald ChallitaUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0009-0002-0883-0749 Joseph HadayaUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0001-9902-0578 Francesco IacovielloElectrochemical Innovation Lab, Department of Chemical Engineering, University College London, London, United Kingdom.ORCID 0000-0003-3564-2380 Ahmad Shah IdilEIT and Neurophysiology Research Group, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.ORCID 0000-0001-7686-3505 Paul R ShearingElectrochemical Innovation Lab, Department of Chemical Engineering, University College London, London, United Kingdom.ORCID 0000-0002-1387-9531 Olujimi A AjijolaUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0001-6197-7593 Jeffrey L ArdellUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0001-9241-0864 Kalyanam ShivkumarUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0002-4121-1766 David HolderEIT and Neurophysiology Research Group, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.ORCID 0000-0003-2755-6124 Kirill AristovichEIT and Neurophysiology Research Group, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.ORCID 0000-0002-2924-5680 University College London · GBLondon Centre for Nanotechnology · GB
Funding
Comprehensive Structural and Functional Mapping of the Mammalian Cardiac Nervous SystemOT2OD023848 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EFIMOV, IGOR R, FOWLKES, CHARLESS · 2016 to 2021
$21.4MNeural Control of Myocardial Excitability at the Nerve Myocyte InterfaceP01HL164311 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALYANAM SHIVKUMAR · 2023 to 2026
$11.3MBioelectric monitoring and neuromodulation of the heartR01HL162921 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALYANAM SHIVKUMAR, Corey B Smith · 2023 to 2026
$3.4MEnhanced quantitative imaging of compound action potentials in multi-fascicular peripheral nerve with fast neural Electrical Impedance Tomography enabled by 3D multi-plane softening bioelectronicsOT2OD026545 · OD · UNIVERSITY COLLEGE LONDON · PI HOLDER, DAVID S · 2018 to 2021
$1.6MNHLBI NIH HHS P01 HL164311NHLBI NIH HHS R01 HL162921NIH HHS OT2 OD023848NIH HHS OT2 OD026545
6 · The paper itselfAbstract
Cardiac disease progression reflects the dynamic interaction between adversely remodeled neurohumoral control systems and an abnormal cardiac substrate. Vagal nerve stimulation (VNS) is an attractive neuromodulatory option to dampen this dynamic interaction; however, it is limited by off-target effects. Spatially-selective VNS (sVNS) offers a promising solution to induce cardioprotection while mitigating off-target effects by specifically targeting pre-ganglionic parasympathetic efferent cardiac fibers. This approach also has the potential to enhance therapeutic outcomes by eliminating time-consuming titration required for optimal VNS. Recent studies have demonstrated the independent modulation of breathing rate, heart rate, and laryngeal contraction through sVNS. However, the spatial organization of afferent and efferent cardiac-related fibers within the vagus nerve remains unexplored. By using trial-and-error sVNS
Indexed as
afferent and efferentcardiacheart failureneuromodulationspatially-selectivevagus nerve stimulation (VNS)
Identifiers
PMID38260584
PMCPMC10802425
OpenAlexW4390704506
What OpenQuestion holds
Textmetadata
LicenceCC BY
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