Evidence map›Paper›PMID 38260542›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Reduced Oxygen Extraction Fraction in Deep Cerebral Veins Associated with Cognitive Impairment in Multiple Sclerosis.

Hasan Sawan, Chenyang Li, Sagar Buch, Evanthia Bernitsas, E Mark Haacke, Yulin Ge, Yongsheng Chen

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hasan SawanDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Chenyang LiDepartment of Radiology, New York University School of Medicine, New York, New York, USA.ORCID 0000-0003-4244-8615
Sagar BuchDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0001-9483-269X
Evanthia BernitsasDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0001-9382-1008
E Mark HaackeDepartment of Radiology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0002-3047-8502
Yulin GeDepartment of Radiology, New York University School of Medicine, New York, New York, USA.ORCID 0000-0002-2320-6031
Yongsheng ChenDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID 0000-0001-7114-5731
Wayne State University · USNew York University · US

Funding

Biomarker development in patients with HNPPR61NS119434 · NINDS · WAYNE STATE UNIVERSITY · PI CHEN, YONGSHENG, LI, JUN · 2022 to 2024
$1.4M
NINDS NIH HHS R61 NS119434
6 · The paper itself

Abstract

Studying the relationship between cerebral oxygen utilization and cognitive impairment is essential to understanding neuronal functional changes in the disease progression of multiple sclerosis (MS). This study explores the potential of using venous susceptibility in internal cerebral veins (ICVs) as an imaging biomarker for cognitive impairment in relapsing-remitting MS (RRMS) patients. Quantitative susceptibility mapping derived from fully flow-compensated MRI phase data was employed to directly measure venous blood oxygen saturation levels (S

Identifiers

PMID38260542
PMCPMC10802653
OpenAlexW4390817850

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.