Evidence map›Paper›PMID 38260459›Full record

ArticlebioRxiv : the preprint server for biology2024

Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation'.

James Taniguchi, Riccardo Melani, Lynne Chantranupong, Michelle J Wen, Ali Mohebi, Joshua Berke, Bernardo Sabatini, Nicolas Tritsch

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

James TaniguchiNeuroscience Institute and Fresco Institute for Parkinson's and Movement Disorders, New York University Grossman School of Medicine, New York, USA.
Riccardo MelaniNeuroscience Institute and Fresco Institute for Parkinson's and Movement Disorders, New York University Grossman School of Medicine, New York, USA.
Lynne ChantranupongDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA.
Michelle J WenDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA.
Ali MohebiDepartment of Neurology, University of California, San Francisco, San Francisco, USA.
Joshua BerkeDepartment of Neurology, University of California, San Francisco, San Francisco, USA.
Bernardo SabatiniDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA.
Nicolas TritschNeuroscience Institute and Fresco Institute for Parkinson's and Movement Disorders, New York University Grossman School of Medicine, New York, USA.ORCID 0000-0003-3181-7681
Howard Hughes Medical Institute · USNew York University · USUniversity of California, San Francisco · US

Funding

Dissecting the Synaptic and Cellular Actions of Dopamine in Vivo - Diversity SupplementR01MH130658 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Tanya Sippy · 2022 to 2026
$3.5M
NIMH NIH HHS R01 MH130658
6 · The paper itself

Abstract

Acetylcholine is widely believed to modulate the release of dopamine in the striatum of mammals. Experiments in brain slices clearly show that synchronous activation of striatal cholinergic interneurons is sufficient to drive dopamine release via axo-axonal stimulation of nicotinic acetylcholine receptors. However, evidence for this mechanism

Identifiers

PMID38260459
PMCPMC10802245
OpenAlexW4390336943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.