Evidence map›Paper›PMID 38260457›Full record

ArticlebioRxiv : the preprint server for biology2024

Reprogramming neuroblastoma by diet-enhanced polyamine depletion.

Sarah Cherkaoui, Lifeng Yang, Matthew McBride, Christina S Turn, Wenyun Lu, Caroline Eigenmann, George E Allen, Olesya O Panasenko, Lu Zhang, Annette Vu and 9 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 6 countries.

Sarah CherkaouiPediatric Cancer Metabolism Laboratory, Children's Research Center, University of Zurich, 8032 Zurich, Switzerland.ORCID 0000-0002-0636-4177
Lifeng YangDepartment of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Matthew McBrideDepartment of Chemistry, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0001-9846-3385
Christina S TurnDivision of Oncology and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0003-3962-6740
Wenyun LuDepartment of Chemistry, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0003-1787-2617
Caroline EigenmannPediatric Cancer Metabolism Laboratory, Children's Research Center, University of Zurich, 8032 Zurich, Switzerland.
George E AllenBioinformatics Support Platform, Faculty of Medicine, University of Geneva 1211, Switzerland.
Olesya O PanasenkoDepartment of Microbiology and Molecular Medicine, Institute of Genetics and Genomics Geneva, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Lu ZhangLudwig Institute for Cancer Research, Princeton Branch, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0002-1580-6774
Annette VuDivision of Oncology and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Kangning LiuDivision of Oncology and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Yimei LiDivision of Oncology and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Om H GandhiDivision of Oncology and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Lea SurreyPerelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Michael WiererProteomics Research Infrastructure, Panum Institute, Blegdamsvej 3B, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-0356-5571
Eileen WhiteLudwig Institute for Cancer Research, Princeton Branch, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0003-2961-3065
Joshua D RabinowitzDepartment of Chemistry, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0002-1247-4727
Michael D HogartyDivision of Oncology and Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0002-9221-4852
Raphael J MorscherPediatric Cancer Metabolism Laboratory, Children's Research Center, University of Zurich, 8032 Zurich, Switzerland.ORCID 0000-0003-3378-9266
Children's Hospital of Philadelphia · USPrinceton University · USRutgers, The State University of New Jersey · USUniversity of Geneva · CHUniversity of Zurich · CHInnsbruck Medical University · ATUniversity of Copenhagen · DK

Funding

Tumor cell metabolism in actionR01CA163591 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI JOSHUA D RABINOWITZ, Eileen P. White · 2012 to 2026
$7.0M
Metabolism in Action: Quantitative Fluxes in MammalsDP1DK113643 · NIDDK · PRINCETON UNIVERSITY · PI RABINOWITZ, JOSHUA D · 2016 to 2020
$5.7M
NCI NIH HHS R01 CA163591NIDDK NIH HHS DP1 DK113643
6 · The paper itself

Abstract

Neuroblastoma is a highly lethal childhood tumor derived from differentiation-arrested neural crest cells

Indexed as

amino acid restrictionargininedietdifluoromethylornithineglutamineornithineornithine aminotransferasepolyaminesprolineProtein translation

Identifiers

PMID38260457
PMCPMC10802427
OpenAlexW4390660782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.