Evidence map›Paper›PMID 38260448›Full record

ArticleResearch square2024

Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity.

Zachary W Davis, Alexandria Busch, Christopher Stewerd, Lyle Muller, John Reynolds

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zachary W DavisThe Salk Institute for Biological Studies, La Jolla, CA, USA. 92037.ORCID 0000-0003-4440-9011
Alexandria BuschDepartment of Applied Mathematics, Western University, London, ON, Canada. N6A 3K7.ORCID 0009-0002-1322-5324
Christopher StewerdDepartment of Applied Mathematics, Western University, London, ON, Canada. N6A 3K7.
Lyle MullerDepartment of Applied Mathematics, Western University, London, ON, Canada. N6A 3K7.ORCID 0000-0001-5165-9890
John ReynoldsThe Salk Institute for Biological Studies, La Jolla, CA, USA. 92037.ORCID 0000-0001-6988-4607
Western University · CASalk Institute for Biological Studies · US

Funding

University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2005 to 2026
$14.6M
Core Grant for Vision ResearchP30EY019005 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D · 2009 to 2018
$7.7M
Spatiotemporal patterns of neural activity and their role in perceptionR01EY028723 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Lyle Edward Muller, JOHN H REYNOLDS · 2018 to 2026
$3.7M
Training Program In Visual NeuroscienceT32EY020503 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D · 2011 to 2020
$1.5M
NEI NIH HHS P30 EY014800NEI NIH HHS P30 EY019005NEI NIH HHS R01 EY028723NEI NIH HHS T32 EY020503
6 · The paper itself

Abstract

Intrinsic, ongoing fluctuations of cortical activity form traveling waves that modulate the gain of sensory-evoked responses and perceptual sensitivity. Several lines of evidence suggest that intrinsic traveling waves (iTWs) may arise, in part, from the coordination of synaptic activity through the recurrent horizontal connectivity within cortical areas, which include long range patchy connections that link neurons with shared feature preferences. In a spiking network model with anatomical topology that incorporates feature-selective patchy connections, which we call the Balanced Patchy Network (BPN), we observe repeated iTWs, which we refer to as

Identifiers

PMID38260448
PMCPMC10802692
OpenAlexW4390770048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.