Evidence map›Paper›PMID 38260373›Full record

ArticlebioRxiv : the preprint server for biology2024

Feedback control of the heat shock response by spatiotemporal regulation of Hsp70.

Rania Garde, Annisa Dea, Madeline F Herwig, David Pincus

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Rania GardeDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL.ORCID 0000-0001-9721-7107
Annisa DeaDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL.ORCID 0000-0002-6292-7106
Madeline F HerwigDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL.
David PincusDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL.ORCID 0000-0002-9651-6858
University of Chicago · US

Funding

Regulatory Dynamics of the Proteostasis NetworkR01GM138689 · NIGMS · UNIVERSITY OF CHICAGO · PI PINCUS, DAVID · 2021 to 2024
$1.3M
NIGMS NIH HHS R01 GM138689
6 · The paper itself

Abstract

Cells maintain homeostasis via dynamic regulation of stress response pathways. Stress pathways transiently induce response regulons via negative feedback loops, but the extent to which individual genes provide feedback has not been comprehensively measured for any pathway. Here, we disrupted induction of each gene in the

Identifiers

PMID38260373
PMCPMC10802473
OpenAlexW4390697675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.