Evidence map›Paper›PMID 38260340›Full record

ArticlebioRxiv : the preprint server for biology2024

Generative modeling of biological shapes and images using a probabilistic

Emily T Winn-Nuñez, Hadley Witt, Dhananjay Bhaskar, Ryan Y Huang, Jonathan S Reichner, Ian Y Wong, Lorin Crawford

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Emily T Winn-NuñezDivision of Applied Mathematics, Brown University, Providence, RI, USA.ORCID 0000-0001-6759-5406
Hadley WittGraduate Program in Pathobiology, Brown University, Providence, RI, USA.
Dhananjay BhaskarDepartment of Genetics, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0001-8068-3101
Ryan Y HuangDepartment of Computer Science, Brown University, Providence, RI USA.ORCID 0000-0001-9920-1037
Jonathan S ReichnerGraduate Program in Pathobiology, Brown University, Providence, RI, USA.ORCID 0000-0002-7349-6321
Ian Y WongGraduate Program in Pathobiology, Brown University, Providence, RI, USA.ORCID 0000-0002-9439-2548
Lorin CrawfordMicrosoft Research, Cambridge, MA, USA.ORCID 0000-0003-0178-8242
Brown University · USProvidence College · USMicrosoft (United States) · USYale University · US

Funding

Brown Respiratory Research Training ProgramT32HL134625 · NHLBI · BROWN UNIVERSITY · PI Elizabeth O Harrington, Sharon Irene Smith Rounds · 2017 to 2026
$5.1M
Use of Biomimicry to Determine the Effect of Sepsis on Neutrophil TractionR01AI116629 · NIAID · RHODE ISLAND HOSPITAL · PI FRANCK, CHRISTIAN, REICHNER, JONATHAN S · 2016 to 2020
$2.1M
NHLBI NIH HHS T32 HL134625NIAID NIH HHS R01 AI116629
6 · The paper itself

Abstract

Understanding morphological variation is an important task in many areas of computational biology. Recent studies have focused on developing computational tools for the task of sub-image selection which aims at identifying structural features that best describe the variation between classes of shapes. A major part in assessing the utility of these approaches is to demonstrate their performance on both simulated and real datasets. However, when creating a model for shape statistics, real data can be difficult to access and the sample sizes for these data are often small due to them being expensive to collect. Meanwhile, the current landscape of generative models for shapes has been mostly limited to approaches that use black-box inference-making it difficult to systematically assess the power and calibration of sub-image models. In this paper, we introduce the

Identifiers

PMID38260340
PMCPMC10802457
OpenAlexW4390765666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.