Evidence map›Paper›PMID 38260319›Full record

ArticlebioRxiv : the preprint server for biology2024

Signaling events at TMEM doorways provide potential targets for inhibiting breast cancer dissemination.

Chinmay R Surve, Camille L Duran, Xianjun Ye, Xiaoming Chen, Yu Lin, Allison S Harney, Yarong Wang, Ved P Sharma, E Richard Stanley, Dianne Cox and 4 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Chinmay R SurveIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
Camille L DuranIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.ORCID 0000-0002-7614-3265
Xianjun YeIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
Xiaoming ChenDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York.
Yu LinDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York.
Allison S HarneyIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
Yarong WangIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
Ved P SharmaDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York.
E Richard StanleyDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York.
Dianne CoxMontefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York.
John C McAuliffeIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
David EntenbergIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
Maja H OktayIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
John S CondeelisIntegrated Imaging Program for Cancer Research, Albert Einstein College of Medicine, Bronx, New York.
Albert Einstein College of Medicine · US

Funding

The Biology of Lung Metastasis in Breast CancerP01CA257885 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Wenjun Guo · 2022 to 2026
$11.9M
TMEM, MENAcalc, and MENAINV as Prognostic and Predictive Markers for Breast Cancer MetastasisR01CA240646 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S, ROHAN, THOMAS E · 2020 to 2024
$4.1M
THE EFFECT OF TUMOR MICROENVIRONMENT ON METASTASISR01CA255153 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S, ENTENBERG, DAVID · 2021 to 2025
$2.5M
High-speed/resolution whole slide scanner supported by two core facilitiesS10OD019961 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S · 2015 to 2015
$326k
Prometastatic Effects of Neoadjuvant Chemotherapy in Breast CancerK99CA237851 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI KARAGIANNIS, GEORGE S · 2019 to 2020
$289k
The role of NF-kappaB signaling in breast cancer metastasisF32CA243350 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DURAN, CAMILLE · 2019 to 2022
$202k
NCI NIH HHS F32 CA243350NCI NIH HHS K99 CA237851NCI NIH HHS P01 CA257885NCI NIH HHS R01 CA240646NCI NIH HHS R01 CA255153NIH HHS S10 OD019961
6 · The paper itself

Abstract

Tumor cell intravasation is essential for metastatic dissemination, but its exact mechanism is incompletely understood. We have previously shown that in breast cancer, the direct and stable association of a tumor cell expressing Mena, a Tie2

Identifiers

PMID38260319
PMCPMC10802469
OpenAlexW4390788142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.