Evidence map›Paper›PMID 38260269›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Multispectral Fundus Photography of Choroidal Nevi with Trans-Palpebral Illumination.

Mojtaba Rahimi, Alfa Rossi, Taeyoon Son, Albert K Dadzie, Behrouz Ebrahimi, Mansour Abtahi, Michael J Heiferman, Xincheng Yao

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mojtaba RahimiDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Alfa RossiDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Taeyoon SonDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Albert K DadzieDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Behrouz EbrahimiDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Mansour AbtahiDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Michael J HeifermanDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, 60612, USA.
Xincheng YaoDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Functional imaging of retinal photoreceptorsR01EY023522 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2014 to 2024
$3.5M
Nonmydriatic ultra-widefield fundus photography employing trans-pars-planar illuminationR01EY029673 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHAN, ROBISON VERNON PAUL, YAO, XINCHENG · 2019 to 2022
$1.8M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LIM, JENNIFER IRENE, YAO, XINCHENG · 2020 to 2023
$1.7M
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2019 to 2022
$1.4M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY029673NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842
6 · The paper itself

Abstract

Purpose: To investigate the spectral characteristics of choroidal nevi and assess the feasibility of quantifying the basal diameter of choroidal nevi using multispectral fundus images captured with trans-palpebral illumination. Methods: The study employed a widefield fundus camera with multispectral (625 nm, 780 nm, 850 nm, and 970 nm) trans-palpebral illumination. Geometric features of choroidal nevi, including border clarity, overlying drusen, and lesion basal diameter, were characterized. Clinical imagers, including scanning laser ophthalmoscopy (SLO), autofluorescence (AF), and optical coherence tomography (OCT), were utilized for comparative assessment. Results: Fundus images captured with trans-palpebral illumination depicted nevi as dark regions with high contrast against the background. Near-infrared (NIR) fundus images provided enhanced visibility of lesion borders compared to visible light fundus images and SLO images. Lesion-background contrast measurements revealed 635 nm SLO at 11% and 625 nm fundus at 42%. Significantly enhanced contrasts were observed in NIR fundus images at 780 nm (73%), 850 nm (63%), and 970 nm (67%). For quantifying the basal diameter of nevi, NIR fundus images at 780 nm and 850 nm yielded a deviation of less than 10% when compared to OCT B-scan measurements. Conclusion: NIR fundus photography with trans-palpebral illumination enhances nevi visibility and boundary definition compared to SLO. Agreement in basal diameter measurements with OCT validates the accuracy and reliability of this method for choroidal nevi assessment.

Identifiers

PMID38260269
PMCPMC10802649
OpenAlexW4390838234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.