Evidence map›Paper›PMID 38260249›Full record

ArticleResearch square2024

Regulation of neuronal circHomer1 biogenesis by PKA/CREB/ERK-mediated pathways and effects of glutamate and dopamine receptor blockade.

Nikolaos Mellios, Grigorios Papageorgiou, Victor Gorgievski, Gabriella Maxson, Megan Hernandez, Madison Otero, Michael Varangis, Michela Dell'Orco, Nora Perrone-Bizzozero, Eleni Tzavara

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nikolaos MelliosUniversity of New Mexico HSC.ORCID 0000-0002-0310-1144
Grigorios PapageorgiouUniversity of New Mexico.ORCID 0000-0002-0309-0932
Victor GorgievskiUniversity of New Mexico.
Gabriella MaxsonUniversity of New Mexico.
Megan HernandezUniversity of New Mexico.
Madison OteroUniversity of New Mexico.
Michael VarangisUniversity of New Mexico.
Michela Dell'OrcoUniversity of New Mexico.
Nora Perrone-BizzozeroUniversity of New Mexico.ORCID 0000-0002-7608-1332
Eleni Tzavara
University of New Mexico · US

Funding

Unfolded Protein Response and Autophagy in T Helper Cell Effector FunctionP20GM121176 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Monica Rosas Lemus · 2017 to 2026
$24.9M
Unraveling the biogenesis and molecular mechanisms of a neuronal-enriched circRNA altered in psychiatric diseaseR01MH125899 · NIMH · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MELLIOS, NIKOLAOS · 2022 to 2023
$1.1M
Role of Psychiatric Disease-associated Circular RNAs in Neuronal Function and CognitionR56MH119150 · NIMH · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MELLIOS, NIKOLAOS · 2019 to 2020
$732k
NIGMS NIH HHS P20 GM121176NIMH NIH HHS R01 MH125899NIMH NIH HHS R56 MH119150
6 · The paper itself

Abstract

There are currently only very few efficacious drug treatments for SCZ and BD, none of which can significantly ameliorate cognitive symptoms. Thus, further research is needed in elucidating molecular pathways linked to cognitive function and antipsychotic treatment. Circular RNAs (circRNAs) are stable brain-enriched non-coding RNAs, derived from the covalent back-splicing of precursor mRNA molecules.

Identifiers

PMID38260249
PMCPMC10802743
OpenAlexW4390796489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.