Evidence map›Paper›PMID 38260246›Full record

ArticlebioRxiv : the preprint server for biology2024

The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study.

Lukas Rier, Natalie Rhodes, Daisie Pakenham, Elena Boto, Niall Holmes, Ryan M Hill, Gonzalo Reina Rivero, Vishal Shah, Cody Doyle, James Osborne and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Lukas RierSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.ORCID 0000-0002-4560-8787
Natalie RhodesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Daisie PakenhamClinical Neurophysiology, Nottingham University Hospitals NHS Trust, Queens Medical Centre, Derby Rd, Lenton, Nottingham NG7 2UH, UK.
Elena BotoSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Niall HolmesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.ORCID 0000-0002-0561-8366
Ryan M HillSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Gonzalo Reina RiveroSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Vishal ShahQuSpin Inc. 331 South 104th Street, Suite 130, Louisville, Colorado, 80027, USA.
Cody DoyleQuSpin Inc. 331 South 104th Street, Suite 130, Louisville, Colorado, 80027, USA.
James OsborneQuSpin Inc. 331 South 104th Street, Suite 130, Louisville, Colorado, 80027, USA.
Richard BowtellSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Margot J TaylorDiagnostic Imaging,The Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada.
Matthew J BrookesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.ORCID 0000-0002-8687-8185
University of Nottingham · GBQuSpin (United States) · USHospital for Sick Children · CANottingham University Hospitals NHS Trust · GB

Funding

High-resolution Non-cryogenic Magnetoencephalography: Systems-Level IntegrationR44MH110288 · NIMH · QUSPIN · PI SHAH, VISHAL K · 2016 to 2022
$5.1M
Next generation Magnetoencephalography for human social neuroscienceR01EB028772 · NIBIB · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LACONTE, STEPHEN M, MONTAGUE, P READ · 2020 to 2023
$2.4M
NIBIB NIH HHS R01 EB028772NIMH NIH HHS R44 MH110288Wellcome Trust
6 · The paper itself

Abstract

Neural oscillations mediate the coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only an important neuroscientific question but could also shed light on the mechanisms underlying neurological and psychiatric disorders. However, measuring the neurodevelopmental trajectory of oscillations has been hampered by confounds from instrumentation. In this paper, we investigate the suitability of a disruptive new imaging platform - Optically Pumped Magnetometer-based magnetoencephalography (OPM-MEG) - to study oscillations during brain development. We show how a unique 192-channel OPM-MEG device, which is adaptable to head size and robust to participant movement, can be used to collect high-fidelity electrophysiological data in individuals aged between 2 and 34 years. Data were collected during a somatosensory task, and we measured both stimulus-induced modulation of beta oscillations in sensory cortex, and whole-brain connectivity, showing that both modulate significantly with age. Moreover, we show that pan-spectral bursts of electrophysiological activity drive task-induced beta modulation, and that their probability of occurrence and spectral content change with age. Our results offer new insights into the developmental trajectory of beta oscillations and provide clear evidence that OPM-MEG is an ideal platform for studying electrophysiology in neurodevelopment.

Indexed as

beta oscillationsBurstsMagnetoencephalographyNeurodevelopmentOptically pumped magnetometers

Identifiers

PMID38260246
PMCPMC10802362
OpenAlexW4390649618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.