Evidence map›Paper›PMID 38260132›Full record

ArticleFrontiers in endocrinology2023

An audit of medullary thyroid carcinoma from a tertiary care hospital in northwest India.

Ananda Mohan Chakraborty, Ashutosh Rai, Rimesh Pal, Soham Mukherjee, Divya Dahiya, Rajinder Kumar, Uma Nahar Saikia, Naresh Kumar Panda, Sanjay Kumar Bhadada, Pinaki Dutta

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ananda Mohan Chakraborty *Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ashutosh Rai *Centre for Endocrinology, William Harvey Research Institute, Queen Marry University of London, London, United Kingdom.
Rimesh PalDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Soham MukherjeeDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Divya DahiyaDepartment of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rajinder KumarDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Uma Nahar SaikiaDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Naresh Kumar PandaDepartment of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sanjay Kumar BhadadaDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Pinaki DuttaDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy originating from parafollicular C cells. It accounts for 5%-10% of all thyroid malignancies. Methods: An ambispective analysis of pathologically proven MTC presented in a tertiary care hospital in northwest India was performed after considering demography, clinical manifestation, Results: Among 2,735 thyroid malignancy cases who presented to our institute in the last 10 years (2012-2022), 78 (3%) had MTC with a mean age of presentation of 43 ± 11 years; 60% of them were female. The median duration of symptoms was 23 months (IQR 12-36 months). The most common presenting complaint was goiter with lymphadenopathy (80.8%). Among the atypical presentations, one each had ectopic Cushing's syndrome, hypertensive crisis in pregnancy due to pheochromocytoma, synchronous chondrosarcoma, and Von Hippel-Lindau disease spectrum. Median calcitonin and carcinoembryonic antigen (CEA) levels at presentation were 1,274 pg/mL ( Conclusion: This study showed that MTC comprises 3% of thyroid malignancies with a female preponderance.

Indexed as

Adrenal Gland NeoplasmsCarcinoma, NeuroendocrineThyroid NeoplasmsAdultFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalPregnancyTertiary Care Centerscalcitoninmedullary thyroid carcinomaneuroendocrine tumorRET mutationtyrosine kinase inhibitor

Identifiers

PMID38260132
PMCPMC10801262
OpenAlexW4390666614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.