Evidence map›Paper›PMID 38259833›Full record

ArticleFrontiers in medicine2023

Randomized controlled trial on healthy volunteers of pharmacokinetic and antimicrobial activity of a novel hydrogel-containing chlorhexidine dressing to prevent catheter-related bloodstream infection.

Emili Masferrer, Laura Riera-Rodríguez, Víctor Farré-Alins, Sandra Vilà de Muga, Francisco-Javier Arroyo-Muñoz, María-Dolores González-Caro

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emili MasferrerDepartment of Dermatology, Hospital Universitari Mútua Terrassa, Terrassa, Spain.
Laura Riera-RodríguezDepartment of Dermatology, Hospital Universitari Mútua Terrassa, Terrassa, Spain.
Víctor Farré-AlinsIberhospitex, S.A., Barcelona, Spain.
Sandra Vilà de MugaIberhospitex, S.A., Barcelona, Spain.
Francisco-Javier Arroyo-MuñozIntensive Care Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain.
María-Dolores González-CaroIntensive Care Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Hospital Universitario Virgen Macarena · ESMútua Terrassa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Catheter-related blood stream infection (CRBSI) is one of the most relevant complications associated to the use of intravascular catheters. In this context, chlorhexidine gluconate (CHG) releasing dressings have been developed to reduce the catheter colonization rate and the risk of infection. The aim of this study is to analyze the release rate of CHG and the antimicrobial activity of a novel CHG-releasing dressing, Oper film Methods: The study was performed in a cohort of 25 healthy volunteers. Two commercially available chlorhexidine-containing dressings were evaluated and compared in this study, Oper film Results: HPLC analysis revealed that both dressings have an equivalent CHG release to the skin 2 days (Oper film Discussion: Data confirm that the recent commercially available dressing Oper film

Indexed as

antimicrobial activitycatheter-related bloodstream infectionchlorhexidinedressingshydrogel

Identifiers

PMID38259833
PMCPMC10800819
OpenAlexW4390665737

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.