ArticleFrontiers in immunology2023
Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors.
Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence.American journal of clinical dermatology · 2026Pooled it
- Clinically Interpretable Deep Learning for Differentiating Vitiligo and Postinflammatory Hypopigmentation: Diagnostic Accuracy Study.JMIR medical informatics · 2026Article
- Dermatologic Conditions and Incident Anxiety in Young Adults: Propensity Score-Matched Retrospective Cohort Study.JMIR dermatology · 2026Article
- Cross-phenotype genome-wide association study supports shared genetic etiology between skin and gastrointestinal tract diseases.Journal of biomedical research · 2026Article
- Keratinocyte-specific H4K12 lactylation drives a non-canonical IL-17-dependent signaling in psoriasis progression in mice.Nature communications · 2025Article
- Enhanced Skin Disease Classification via Dataset Refinement and Attention-Based Vision Approach.Bioengineering (Basel, Switzerland) · 2025Article
- Gender-related Therapeutical Response to Apremilast: New Insights in a Tailored Management of Psoriasis.Dermatology practical & conceptual · 2025Article
- Burden of immune-related skin diseases worldwide, 1991-2021: insights and prediction from the Global Burden of Disease Study.Frontiers in immunology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Introduction: The utilization of large-scale claims databases has greatly improved the management, accessibility, and integration of extensive medical data. However, its potential for systematically identifying comorbidities in the context of skin diseases remains unexplored. Methods: This study aims to assess the capability of a comprehensive claims database in identifying comorbidities linked to 14 specific skin and skin-related conditions and examining temporal changes in their association patterns. This study employed a retrospective case-control cohort design utilizing 13 million skin/skin-related patients and 2 million randomly sampled controls from Optum's de-identified Clinformatics Results: Using the established type-2 diabetes (T2D) and psoriasis comorbidity as example, we demonstrated the association is significant (P-values<1x10 Discussion: The findings highlight the potential of utilizing comprehensive claims databases in advancing research and improving patient care in dermatology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.