Evidence map›Paper›PMID 38258819›Full record

Trial reportSubstance use & addiction journal2024

Results From the POINT Pragmatic Randomized Trial: An Emergency Department-Based Peer Support Specialist Intervention to Increase Opioid Use Disorder Treatment Linkage and Reduce Recurrent Overdose.

Dennis P Watson, Martha Tillson, Lisa Taylor, Huiping Xu, Fangqian Ouyang, Francesca L Beaudoin, Daniel O'Donnell, Alan B McGuire

Open access · greenAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Substance use & addiction journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Inpatient utilization among Medicaid members with substance use disorder in Oregon.Substance abuse treatment, prevention, and policy · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Peer support for patients with opioid use disorder in the emergency department: A narrative review.Journal of the American College of Emergency Physicians open · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Dennis P WatsonChestnut Health Systems, Lighthouse Institute, Chicago, IL, USA.ORCID 0000-0001-7208-5160
Martha TillsonCenter on Drug and Alcohol Research, University of Kentucky, Lexington, KY, USA.
Lisa TaylorChestnut Health Systems, Lighthouse Institute, Chicago, IL, USA.
Huiping XuDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.
Fangqian OuyangDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.
Francesca L BeaudoinFrancesca Beaudoin, Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Daniel O'DonnellDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Alan B McGuireDepartment of Psychology, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.
Indiana University School of MedicineChestnut Health Systems · USBrown University · USUniversity of Indianapolis · USUniversity of Kentucky · US

Funding

Project POINT: Effectiveness and Scalability of an Overdose Survivor InterventionR33DA045850 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI MCGUIRE, ALAN BENJAMIN, WATSON, DENNIS PAUL · 2018 to 2020
$1.9M
Project POINT: Effectiveness and Scalability of an Overdose Survivor InterventionR21DA045850 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI WATSON, DENNIS PAUL · 2017 to 2017
$288k
NIDA NIH HHS R21 DA045850NIDA NIH HHS R33 DA045850
6 · The paper itself

Abstract

backgroundPeople with opioid use disorder (OUD) frequently present at the emergency department (ED), a potentially critical point for intervention and treatment linkage. Peer recovery support specialist (PRSS) interventions have expanded in US-based EDs, although evidence supporting such interventions has not been firmly established.

methodsResearchers conducted a pragmatic trial of POINT (Project Planned Outreach, Intervention, Naloxone, and Treatment), an ED-initiated intervention for harm reduction and recovery coaching/treatment linkage in 2 Indiana EDs. Cluster randomization allocated patients to the POINT intervention (n

resultsPOINT and standard care participants did not differ significantly on any outcomes measured. Participants who presented to the ED for overdose had significantly lower scores (3.5 vs 4.2,

conclusionsThis is the first randomized trial investigating overdose outcomes for an ED peer recovery support specialist intervention. Though underpowered, results suggest no benefit of PRSS services over standard care. Given the scope of PRSS, future work in this area should assess more recovery- and harm reduction-oriented outcomes, as well as the potential benefits of integrating PRSS within multimodal ED-based interventions for OUD.

Indexed as

Emergency Service, HospitalOpioid-Related DisordersPeer GroupAdultDrug OverdoseFemaleHarm ReductionHumansIndianaMaleMiddle AgedNaloxoneNarcotic AntagonistsOpiate OverdoseNaloxoneNarcotic Antagonistsemergency departmentmedications for opioid use disorderopioid poisoningopioid use disorderoverdosepeer support

Identifiers

PMID38258819
PMCPMC11179981
OpenAlexW4391144982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.