Evidence map›Paper›PMID 38258773›Full record

ArticleCurrent hypertension reviews2024

Association of COVID-19 and Arterial Stiffness Assessed using Cardiovascular Index (CAVI).

Valery Podzolkov, Anna Bragina, Aida Tarzimanova, Lyubov Vasilyeva, Ilya Shvedov, Natalya Druzhinina, Yulia Rodionova, Tatiana Ishina, Iuliia Akyol, Valentina Maximova and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Current hypertension reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Valery PodzolkovDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0002-0758-5609
Anna BraginaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0002-2699-1610
Aida TarzimanovaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0001-9536-8307
Lyubov VasilyevaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0001-5730-7837
Ilya ShvedovDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0001-9722-6097
Natalya DruzhininaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0001-8397-0210
Yulia RodionovaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0003-3461-6703
Tatiana IshinaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0001-7720-0770
Iuliia AkyolDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0009-0009-5255-8464
Valentina MaximovaDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0009-0004-6806-4198
Alexandr CherepanovDepartment of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID 0000-0002-7971-7711
Sechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 is characterized by an acute inflammatory response with the formation of endothelial dysfunction and may affect arterial stiffness. Studies of cardio-ankle vascular index in COVID-19 patients with considered cardiovascular risk factors have not been conducted.

objectiveThe purpose of our study was to assess the association between cardio-ankle vascular index and COVID-19 in hospitalized patients adjusted for known cardiovascular risk factors.

methodsA cross-sectional study included 174 people hospitalized with a diagnosis of moderate COVID-19 and 94 people without COVID-19. Significant differences in the cardio-ankle vascular index values measured by VaSera VS - 1500N between the two groups were analyzed using parametric (Student's t-criterion) and nonparametric (Mann-Whitney) criteria. Independent association between COVID-19 and an increased cardio-ankle vascular index ≥ 9.0 adjusted for known cardiovascular risk factors was assessed by multivariate logistic regression.

resultsThere were significantly higher values of the right cardio-ankle vascular index 8.10 [7.00;9.40] and the left cardio-ankle vascular index 8.10 [6.95;9.65] in patients undergoing inpatient treatment for COVID-19 than in the control group - 7.55 [6.60;8.60] and 7.60 [6.60;8.70], respectively. A multivariate logistic regression model adjusted for age, hypertension, plasma glucose level, glomerular filtration rate and diabetes mellitus showed a significant association between increased cardio-ankle vascular index and COVID-19 (OR 2.41 [CI 1.09;5.30]).

conclusionHospitalized patients with COVID-19 had significantly higher cardio-ankle vascular index values compared to the control group. An association between an increased cardio-ankle vascular index and COVID-19 was revealed, independent of age, hypertension, plasma glucose level, glomerular filtration rate and diabetes mellitus.

Indexed as

Cardio Ankle Vascular IndexCOVID-19Vascular StiffnessAdultAgedCardiovascular DiseasesCross-Sectional StudiesFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedRisk AssessmentRisk FactorsSARS-CoV-2Arterial stiffnesscardiovascular indexcardiovascular risk factorsCOVID-19diabetes mellitus.hypertension

Identifiers

PMID38258773
PMCPMC11092554
OpenAlexW4391137306

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.