Evidence map›Paper›PMID 38258535›Full record

ArticlePain medicine (Malden, Mass.)2024

Relationship between insomnia and pain in patients with chronic orofacial pain.

Anna Alessandri-Bonetti, Linda Sangalli, Ian A Boggero

Open access · bronzeAbstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. The interplay of sleep disorders and orofacial pain: A systematic review.Journal of clinical and experimental dentistry · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Anna Alessandri-BonettiDivision of Orofacial Pain, Department of Oral Health Science, University of Kentucky, College of Dentistry, Lexington, KY 40536, United States.ORCID 0000-0003-2210-1403
Linda SangalliCollege of Dental Medicine-Illinois, Midwestern University, Downers Grove, IL 60515, United States.
Ian A BoggeroDivision of Orofacial Pain, Department of Oral Health Science, University of Kentucky, College of Dentistry, Lexington, KY 40536, United States.ORCID 0000-0001-8891-0292
Midwestern University · USUniversità Cattolica del Sacro Cuore · ITUniversity of Kentucky · US

Funding

Initial Evidence for a Brief Psychological Telehealth Intervention for Patients with Chronic Masticatory Muscle PainK23DE031807 · NIDCR · UNIVERSITY OF KENTUCKY · PI BOGGERO, IAN ANDRES · 2023 to 2025
$640k
NIDCR NIH HHS K23 DE031807NIH HHS K23DE031807
6 · The paper itself

Abstract

objectiveFew studies have investigated specific associations between insomnia and orofacial pain (OFP). The aim of this cross-sectional study was to examine relationships of insomnia with pain, mental health, and physical health variables among treatment-seeking patients with chronic OFP.

methodsOFP diagnosis, demographics, insomnia symptoms, pain intensity, interference, and duration, mental health measures, and number of medical comorbidities were extracted from the medical records of 450 patients receiving an initial appointment at a university-affiliated tertiary OFP clinic. T-tests compared differences between patients with and without insomnia symptomatology, and between patients with different insomnia subtypes (delayed onset/early wakening).

resultsCompared to patients without insomnia, those with elevated insomnia symptomatology (45.1%) reported higher pain intensity (60.70 ± 20.61 vs 44.15 ± 21.69; P < .001) and interference (43.81 ± 29.84 vs 18.40 ± 23.43; P < 0.001), depression/anxiety symptomatology (5.53 ± 3.32 vs 2.72 ± 2.66; P < 0.001), dissatisfaction with life (21.63 ± 6.95 vs 26.50 ± 6.21; P < .001), and number of medical comorbidities (6.72 ± 5.37 vs 4.37 ± 4.60; P < .001). Patients with Sleep Onset Latency insomnia (SOL-insomnia) (N = 76) reported higher pain intensity (t = 3.57; P < 0.001), and pain interference (t = 4.46; P < .001) compared to those without SOL-insomnia. Those with Early Morning Awakening insomnia (EMA-insomnia) (N = 71) did not significantly differ from those without EMA-insomnia on any of the variables. Differences remained significant after adjusting for age, sex, primary OFP diagnosis, and pain intensity.

conclusionsInsomnia is associated with pain outcomes and should be appropriately managed when treating patients with chronic OFP.

Indexed as

Chronic PainFacial PainSleep Initiation and Maintenance DisordersAdultAgedComorbidityCross-Sectional StudiesDepressionFemaleHumansMaleMiddle Ageddelayed-sleep onset insomniaearly-awakening insomniainsomniaorofacial pain

Identifiers

PMID38258535
PMCPMC11063747
OpenAlexW4391138527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.