Evidence map›Paper›PMID 38258131›Full record

ArticlePharmaceutics2024

Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca

Irene Pachón-Angona, Paul J Bernard, Alexey Simakov, Maciej Maj, Krzysztof Jozwiak, Anna Novotna, Carina Lemke, Michael Gütschow, Helene Martin, María-Jesús Oset-Gasque and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Irene Pachón-AngonaUniversité de Franche-Comté, UMR INSERM 1322 LINC, F-25000 Besançon, France.
Paul J BernardUniversité de Franche-Comté, UMR INSERM 1322 LINC, F-25000 Besançon, France.
Alexey SimakovUniversité de Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France.ORCID 0000-0002-3076-0030
Maciej MajDepartment of Biopharmacy, Medical University of Lublin, ul. W. Chodzki 4a, 20-093 Lublin, Poland.
Krzysztof JozwiakDepartment of Biopharmacy, Medical University of Lublin, ul. W. Chodzki 4a, 20-093 Lublin, Poland.ORCID 0000-0001-6018-5092
Anna NovotnaPharmaceutical Institut, An der Immenburg 4, D-53121 Bonn, Germany.
Carina LemkePharmaceutical Institut, An der Immenburg 4, D-53121 Bonn, Germany.
Michael GütschowPharmaceutical Institut, An der Immenburg 4, D-53121 Bonn, Germany.ORCID 0000-0002-9376-7897
Helene MartinUniversité de Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France.ORCID 0000-0001-8318-3858
María-Jesús Oset-GasqueDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.ORCID 0000-0002-7223-0222
José-Marco ContellesLaboratory of Medicinal Chemistry (IQOG, CSIC) C/Juan de la Cierva 3, 28006 Madrid, Spain.
Lhassane IsmailiUniversité de Franche-Comté, UMR INSERM 1322 LINC, F-25000 Besançon, France.ORCID 0000-0002-6013-3150
Inserm · FRMedical University of Lublin · PLUniversidad Complutense de Madrid · ESInstituto de Salud Carlos III · ES

Funding

Centre Bourgogne-Franche-Comté 2022Y-13659 and 13660 Accurate Project
6 · The paper itself

Abstract

This work relates to the design and synthesis of a series of novel multi-target directed ligands (MTDLs), i.e., compounds

Indexed as

Alzheimer’s diseaseantioxidant response elementcalcium channel inhibitorsORACproteases inhibitors

Identifiers

PMID38258131
PMCPMC10819521
OpenAlexW4390954529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.