Evidence map›Paper›PMID 38258099›Full record

ReviewPharmaceutics2024

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery.

Ming Song, Adila Aipire, Elzira Dilxat, Jianmin Li, Guoyu Xia, Ziwen Jiang, Zhongxiong Fan, Jinyao Li

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Frontiers in nutrition · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ming SongInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.
Adila AipireInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.
Elzira DilxatInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.
Jianmin LiInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.
Guoyu XiaInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.
Ziwen JiangDepartment of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100006, China.
Zhongxiong FanInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.ORCID 0000-0001-5751-9530
Jinyao LiInstitute of Materia Medica & College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.ORCID 0000-0002-3295-6096
Xinjiang Institute of Materia Medica · CNCapital Medical University · CN

Funding

Key research and development program in Xinjiang Uygur Autonomous Region 2022B02058Key research and development program in Xinjiang Uygur Autonomous Region 2022B03018-5National Natural Science Foundation of China 32000625National Natural Science Foundation of China 32360185Opening Project of Xinjiang Uyghur drug Key Laboratory wysys-2023-01the Natural Science Foundation of Xinjiang Uygur Autonomous Region 2022D01C698The Xinjiang Uygur Autonomous Region universities basic research funds research projects-cultivation projects XJEDU2023P017Xinjiang Uygur Autonomous Region Tianchi Talent Introduction Program-Young Doctor 51052300514
6 · The paper itself

Abstract

Clinical drug administration aims to deliver drugs efficiently and safely to target tissues, organs, and cells, with the objective of enabling their therapeutic effects. Currently, the main approach to enhance a drug's effectiveness is ensuring its efficient delivery to the intended site. Due to the fact that there are still various drawbacks of traditional drug delivery methods, such as high toxicity and side effects, insufficient drug specificity, poor targeting, and poor pharmacokinetic performance, nanocarriers have emerged as a promising alternative. Nanocarriers possess significant advantages in drug delivery due to their size tunability and surface modifiability. Moreover, nano-drug delivery systems have demonstrated strong potential in terms of prolonging drug circulation time, improving bioavailability, increasing drug retention at the tumor site, decreasing drug resistance, as well as reducing the undesirable side effects of anticancer drugs. Numerous studies have focused on utilizing polysaccharides as nanodelivery carriers, developing delivery systems based on polysaccharides, or exploiting polysaccharides as tumor-targeting ligands to enhance the precision of nanoparticle delivery. These types of investigations have become commonplace in the academic literature. This review aims to elucidate the preparation methods and principles of polysaccharide gold nanocarriers. It also provides an overview of the factors that affect the loading of polysaccharide gold nanocarriers with different kinds of drugs. Additionally, it outlines the strategies employed by polysaccharide gold nanocarriers to improve the delivery efficiency of various drugs. The objective is to provide a reference for further development of research on polysaccharide gold nanodelivery systems.

Indexed as

drug deliverygold nanoparticlesnanocarriersoncotherapypolysaccharides

Identifiers

PMID38258099
PMCPMC10820823
OpenAlexW4390704141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.