Evidence map›Paper›PMID 38258063›Full record

ArticlePharmaceutics2023

Comparative Antioxidant and Antimicrobial Activities of Several Conifer Needles and Bark Extracts.

Diana Ionela Popescu Stegarus, Adina Frum, Carmen Maximiliana Dobrea, Ramona Cristea, Felicia Gabriela Gligor, Laura Gratiela Vicas, Roxana Elena Ionete, Nicoleta Anca Sutan, Cecilia Georgescu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Polymers · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Needle extracts ofFrontiers in pharmacology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Diana Ionela Popescu StegarusNational Research and Development Institute for Cryogenic and Isotopic Technologies-ICSI Ramnicu Valcea, 240050 Ramnicu Valcea, Romania.ORCID 0000-0002-3442-3760
Adina FrumPreclinical Department, Faculty of Medicine, "Lucian Blaga" University of Sibiu, 550169 Sibiu, Romania.ORCID 0000-0003-4874-0430
Carmen Maximiliana DobreaPreclinical Department, Faculty of Medicine, "Lucian Blaga" University of Sibiu, 550169 Sibiu, Romania.ORCID 0000-0002-9913-1750
Ramona CristeaDepartment of Agricultural Sciences and Food Engineering, "Lucian Blaga" University of Sibiu, 550012 Sibiu, Romania.ORCID 0000-0001-8411-1207
Felicia Gabriela GligorPreclinical Department, Faculty of Medicine, "Lucian Blaga" University of Sibiu, 550169 Sibiu, Romania.ORCID 0000-0003-3167-9864
Laura Gratiela VicasDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.ORCID 0000-0001-5328-333X
Roxana Elena IoneteNational Research and Development Institute for Cryogenic and Isotopic Technologies-ICSI Ramnicu Valcea, 240050 Ramnicu Valcea, Romania.ORCID 0000-0002-0789-6108
Nicoleta Anca SutanDepartment of Natural Sciences, Piteşti University Center, National University of Science and Technology Politechnica Bucharest, 110040 Pitesti, Romania.
Cecilia GeorgescuDepartment of Agricultural Sciences and Food Engineering, "Lucian Blaga" University of Sibiu, 550012 Sibiu, Romania.ORCID 0000-0003-4804-1138
Lucian Blaga University of Sibiu · RONational Institute for Research and Development of Isotopic and Molecular Technologies · ROUniversity of Oradea · ROUniversity of Pitesti · RO

Funding

Lucian Blaga University of Sibiu LBUS-IRG-2022-08/No. 2910 - 18 July 2022Romanian Ministry of Research Innovation and Digitalization, under Program 1-Development of the national research and development system, Subprogram 1.1. Institutional performance-Projects to finance excellence in RDI 19PFE/30.12.2021
6 · The paper itself

Abstract

Nowadays, an increased concern regarding using natural products for their health benefits can be observed. The aim of this study was to assess and compare several phenolic compounds found in 15- to 60-year-old Douglas fir, silver fir, larch, pine, and spruce needle and bark extracts and to evaluate their antioxidant and antimicrobial activities. Spectrophotometric assays were used to determine the total polyphenol content and the antioxidant activity that was assessed by using the DPPH• radical scavenging assay (RSA), the ferric reducing antioxidant power assay (FRAP), and the ABTS•+ radical cation scavenging assay (ABTS). The phytochemical content was determined by using high-performance liquid chromatography, and the antimicrobial activity was determined by assessing the minimal inhibition concentration (MIC). The results of the study show a total polyphenol content of 62.45-109.80 mg GAE/g d.w. and an antioxidant activity of 91.18-99.32% for RSA, 29.16-35.74 µmol TE/g d.w. for FRAP, and 38.23-53.57 µmol TE/g d.w. for ABTS. The greatest quantity of phenolic compound for most of the extracts was for (+)-catechin, and it had values between 165.79 and 5343.27 µg/g d.w. for these samples. The antimicrobial inhibition for all the extracts was the strongest for

Indexed as

antimicrobial activityantioxidant activityDouglas firlarchpinepolyphenolssilver firspruce

Identifiers

PMID38258063
PMCPMC10821083
OpenAlexW4390338569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.