Evidence map›Paper›PMID 38257957›Full record

ArticleMicroorganisms2024

Cold Atmospheric Helium Plasma in the Post-COVID-19 Era: A Promising Tool for the Disinfection of Silicone Endotracheal Prostheses.

Diego Morais da Silva, Fellype Do Nascimento, Noala Vicensoto Moreira Milhan, Maria Alcionéia Carvalho de Oliveira, Paulo Francisco Guerreiro Cardoso, Daniel Legendre, Fabio Gava Aoki, Konstantin Georgiev Kostov, Cristiane Yumi Koga-Ito

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Diego Morais da SilvaInstitute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12227-010, SP, Brazil.ORCID 0000-0003-0271-9142
Fellype Do NascimentoFaculty of Engineering, São Paulo State University (UNESP), Guaratinguetá 12516-410, SP, Brazil.ORCID 0000-0002-8641-9894
Noala Vicensoto Moreira MilhanInstitute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12227-010, SP, Brazil.ORCID 0000-0002-9137-8476
Maria Alcionéia Carvalho de OliveiraInstitute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12227-010, SP, Brazil.ORCID 0000-0002-7060-7604
Paulo Francisco Guerreiro CardosoDivision of Thoracic Surgery, Instituto do Coração, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 01246-903, SP, Brazil.
Daniel LegendreAdib Jatene Foundation, Dante Pazzanese Institute of Cardiology, São Paulo 04012-909, SP, Brazil.
Fabio Gava AokiInstitute of Science and Technology, Federal University of São Paulo (UNIFESP), São José dos Campos 12231-280, SP, Brazil.ORCID 0000-0003-3387-5121
Konstantin Georgiev KostovFaculty of Engineering, São Paulo State University (UNESP), Guaratinguetá 12516-410, SP, Brazil.ORCID 0000-0002-9821-8088
Cristiane Yumi Koga-ItoInstitute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12227-010, SP, Brazil.ORCID 0000-0002-2416-2173
Universidade Estadual Paulista (Unesp) · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInstituto Dante Pazzanese de Cardiologia · BRUniversidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 0National Council for Scientific and Technological Development 308127/2018-8National Council for Scientific and Technological Development 309762/2021-9São Paulo Research Foundation 2019/05856-7São Paulo Research Foundation 2021/02680-5
6 · The paper itself

Abstract

Despite the excellent properties of silicone endotracheal prostheses, their main limitation is the formation of a polymicrobial biofilm on their surfaces. It can cause local inflammation, interfering with the local healing process and leading to further complications in the clinical scenario. The present study evaluated the inhibitory effect of cold atmospheric plasma (CAP) on multispecies biofilms grown on the silicone protheses' surfaces. In addition to silicone characterization before and after CAP exposure, CAP cytotoxicity on immortalized human bronchial epithelium cell line (BEAS-2B) was evaluated. The aging time test reported that CAP could temporarily change the silicone surface wetting characteristics from hydrophilic (80.5°) to highly hydrophilic (<5°). ATR-FTIR showed no significant alterations in the silicone surficial chemical composition after CAP exposure for 5 min. A significant log reduction in viable cells in monospecies biofilms (log CFU/mL) of

Indexed as

COVID-19endotracheal tubesmultispecies biofilmnon-thermal plasmasilicone prosthesis

Identifiers

PMID38257957
PMCPMC10819505
OpenAlexW4390732522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.