Evidence map›Paper›PMID 38257876›Full record

ArticleMicroorganisms2023

Drug Resistance and Molecular Characteristics of Carbapenem-Resistant OXA-48-Producing

Min Ye, Lei Liu, Bin Liu, Xiangdong Zhou, Qi Li

RetractedAbstract readRetracted Publication
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Min YeInternational School of Nursing, Hainan Medical University, Haikou 571199, China.
Lei LiuDepartment of Respiratory Medicine, The First Affiliated Hospital of Hainan Medical University, Haikou 570100, China.
Bin LiuDepartment of Respiratory Medicine, The First Affiliated Hospital of Hainan Medical University, Haikou 570100, China.
Xiangdong ZhouDepartment of Respiratory Medicine, The First Affiliated Hospital of Hainan Medical University, Haikou 570100, China.
Qi LiDepartment of Respiratory Medicine, The First Affiliated Hospital of Hainan Medical University, Haikou 570100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence and global spread of carbapenem-resistant hypervirulent

methodsOXA-48-producing hvKP strains were collected from clinical specimens at the First Affiliated Hospital of Hainan Medical University from January 2022 to March 2023. Hypervirulent strains were tested for virulence in a mouse lethality study and underwent whole genome sequencing to identify genomic features.

resultsA total of 42 unique OXA-48-bearing

conclusionsOur study highlighted the two evolutionary pathways of OXA-48-producing hvKP strains and confirmed their virulence through in vivo testing. Ceftazidime/avibactam may be a viable option for treating OXA-48-producing hvKP strains.

Indexed as

carbapenemasehypervirulent strainKlebsiella pneumoniaeOXA-48

Identifiers

PMID38257876
PMCPMC10820085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.