Evidence map›Paper›PMID 38257846›Full record

ArticleMicroorganisms2023

Pegivirus Detection in Cerebrospinal Fluid from Patients with Central Nervous System Infections of Unknown Etiology in Brazil by Viral Metagenomics.

Rita de Cássia Compagnoli Carmona, Audrey Cilli, Antonio Charlys da Costa, Fabricio Caldeira Reis, Élcio Leal, Fabiana Cristina Pereira Dos Santos, Bráulio Caetano Machado, Cristina Santiago Lopes, Ana Maria Sardinha Afonso, Maria do Carmo Sampaio Tavares Timenetsky

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rita de Cássia Compagnoli CarmonaEnteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.ORCID 0000-0002-9174-3234
Audrey CilliEnteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.ORCID 0000-0002-1642-5252
Antonio Charlys da CostaInstitute of Tropical Medicine, University of São Paulo, Sao Paulo 05403-000, Brazil.ORCID 0000-0001-5516-5177
Fabricio Caldeira ReisEnteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.ORCID 0000-0002-3721-1704
Élcio LealInstitute of Biological Sciences, Federal University of Pará, Belem 66075-000, Brazil.ORCID 0000-0003-3463-0492
Fabiana Cristina Pereira Dos SantosRespiratory Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.
Bráulio Caetano MachadoEnteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.
Cristina Santiago LopesRespiratory Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.
Ana Maria Sardinha AfonsoRespiratory Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.
Maria do Carmo Sampaio Tavares TimenetskyVirology Center, Adolfo Lutz Institute, Sao Paulo 01246-900, Brazil.
Instituto Adolfo Lutz · BRUniversidade de São Paulo · BRUniversidade Federal do Pará · BR

Funding

Governo do Estado de São Paulo Fundo Especial de Saúde para Imunização em Massa e Controle de Doenças (FESIMA) SES-PRC-2020/42261 (#CAF107/2020, #CAF 050/2021 and #CAF 060/2022)São Paulo Research Foundation #2018/21193-5 e #2017/50333-7
6 · The paper itself

Abstract

Metagenomic next-generation sequencing (mNGS) methodology serves as an excellent supplement in cases where diagnosis is challenging to establish through conventional laboratory tests, and its usage is increasingly prevalent. Examining the causes of infectious diseases in the central nervous system (CNS) is vital for understanding their spread, managing outbreaks, and effective patient care. In a study conducted in the state of São Paulo, Brazil, cerebrospinal fluid (CSF) samples from 500 patients with CNS diseases of indeterminate etiology, collected between 2017 and 2021, were analyzed. Employing a mNGS approach, we obtained the complete coding sequence of

Indexed as

central nervous system infectionscerebrospinal fluidmetagenomicpegivirus human

Identifiers

PMID38257846
PMCPMC10818654
OpenAlexW4390111993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.