Evidence map›Paper›PMID 38257258›Full record

ArticleMolecules (Basel, Switzerland)2024

Rational Design of Palladium(II) Indenyl and Allyl Complexes Bearing Phosphine and Isocyanide Ancillary Ligands with Promising Antitumor Activity.

Enrica Bortolamiol, Eleonora Botter, Enrico Cavarzerani, Matteo Mauceri, Nicola Demitri, Flavio Rizzolio, Fabiano Visentin, Thomas Scattolin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Enrica BortolamiolDepartment of Molecular Sciences and Nanosystems, Università Ca' Foscari, Campus Scientifico, Via Torino 155, 30174 Venezia, Italy.
Eleonora BotterDepartment of Molecular Sciences and Nanosystems, Università Ca' Foscari, Campus Scientifico, Via Torino 155, 30174 Venezia, Italy.
Enrico CavarzeraniDepartment of Molecular Sciences and Nanosystems, Università Ca' Foscari, Campus Scientifico, Via Torino 155, 30174 Venezia, Italy.
Matteo MauceriDepartment of Molecular Sciences and Nanosystems, Università Ca' Foscari, Campus Scientifico, Via Torino 155, 30174 Venezia, Italy.ORCID 0000-0002-5299-994X
Nicola DemitriElettra-Sincrotrone Trieste, Area Science Park, S.S. 14 Km 163.5 Basovizza, 34149 Trieste, Italy.
Flavio RizzolioDepartment of Molecular Sciences and Nanosystems, Università Ca' Foscari, Campus Scientifico, Via Torino 155, 30174 Venezia, Italy.ORCID 0000-0002-3400-4363
Fabiano VisentinDepartment of Molecular Sciences and Nanosystems, Università Ca' Foscari, Campus Scientifico, Via Torino 155, 30174 Venezia, Italy.
Thomas ScattolinDipartimento di Scienze Chimiche, Università Degli Studi di Padova, Via Marzolo 1, 35131 Padova, Italy.ORCID 0000-0001-7345-9670
Ca' Foscari University of Venice · ITElettra-Sincrotrone Trieste S.C.p.A. · ITUniversity of Padua · IT

Funding

Italian Association for Cancer Research IG23566
6 · The paper itself

Abstract

A new class of palladium-indenyl complexes characterized by the presence of one bulky alkyl isocyanide and one aryl phosphine serving as ancillary ligands has been prepared, presenting high yields and selectivity. All the new products were completely characterized using spectroscopic and spectrometric techniques (NMR, FT-IR, and HRMS), and, for most of them, it was also possible to define their solid-state structures via X-ray diffractometry, revealing that the indenyl fragment always binds to the metal centre with a hapticity intermediate between ƞ

Indexed as

Breast NeoplasmsOvarian NeoplasmsPhosphinesCell Line, TumorCisplatinCyanidesFemaleHumansLigandsPalladiumSpectroscopy, Fourier Transform InfraredCisplatinCyanidesLigandsPalladiumphosphinePhosphinesantitumor activityisocyanide ligandsmetallodrugsovarian cancerpalladium indenyl complexesphosphine ligands

Identifiers

PMID38257258
PMCPMC10819880
OpenAlexW4390701767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.