Evidence map›Paper›PMID 38257245›Full record

ReviewMolecules (Basel, Switzerland)2024

Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment-Progresses in Their Use in Combined Cancer Therapy.

Adrián Povo-Retana, Rodrigo Landauro-Vera, Carlota Alvarez-Lucena, Marta Cascante, Lisardo Boscá

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Marine natural products.Natural product reports · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Pegylated liposomal doxorubicin combined with trabectedin as a treatment option in uterine sarcomas: a single-institution retrospective analysis.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024
    Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adrián Povo-RetanaInstituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.
Rodrigo Landauro-VeraInstituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.ORCID 0000-0001-5364-6575
Carlota Alvarez-LucenaInstituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.
Marta CascanteDepartment of Biochemistry and Molecular Biomedicine-Institute of Biomedicine (IBUB), Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-2062-4633
Lisardo BoscáInstituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.ORCID 0000-0002-0253-5469
Instituto de Investigaciones Biomédicas Sols-Morreale · ESInstituto de Salud Carlos III · ES

Funding

RECEPTORS MEDIATING DRUG DEPENDENCER01DA007223 · NIDA · UNIVERSITY OF TORONTO · PI GEORGE, SUSAN R · 1991 to 2013
$2.5M
Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares CB16/11/00222"); Comunidad de Madrid Programa Biociencias S2022-BMD-7223Enfermedades Hepáticas y Digestivas from the Instituto de Salud Carlos III (co-financed by the European Development Regional Fund "A Way to Achieve Europe", by the "European Union" and by the "European Union NextGeneration EU/PRTR") CB17/04/00023MICIN/AEI 13039/501100011033 PID2020-113238RB-I00
6 · The paper itself

Abstract

Trabectedin (TRB) and Lurbinectedin (LUR) are alkaloid compounds originally isolated from

Indexed as

CarbolinesHeterocyclic Compounds, 4 or More RingsOvarian NeoplasmsTumor MicroenvironmentAdultFemaleHumansNeoplasm Recurrence, LocalTrabectedinCarbolinesHeterocyclic Compounds, 4 or More RingsPM 01183Trabectedinadaptative immunitycombined therapiesecteinascidinsinnate immunitylurbinectedinlymphocytesmacrophagesmolecular oncologytrabectedin

Identifiers

PMID38257245
PMCPMC10820391
OpenAlexW4390780682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.