Evidence map›Paper›PMID 38257124›Full record

ArticleNutrients2024

Improving the Diagnosis of Dermatitis Herpetiformis Using the Intraepithelial Lymphogram.

Fernando Fernández-Bañares, Laura Crespo, Montserrat Planella, Sergio Farrais, Sandra Izquierdo, Natalia López-Palacios, Garbiñe Roy, Judith Vidal, Concepción Núñez

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Fernando Fernández-BañaresDepartment of Gastroenterology, Hospital Universitari Mutua Terrassa, 08221 Terrasa, Spain.ORCID 0000-0002-1489-504X
Laura CrespoDepartment of Gastroenterology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Montserrat PlanellaDepartment of Gastroenterology, Hospital Arnau Vilanova, 25198 Lleida, Spain.
Sergio FarraisDepartment of Gastroenterology, Hospital Fundación Jiménez Díaz, 28040 Madrid, Spain.
Sandra IzquierdoDepartment of Gastroenterology, Hospital Clínico Universitario, 47003 Valladolid, Spain.
Natalia López-PalaciosDepartment of Gastroenterology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos, 28040 Madrid, Spain.
Garbiñe RoyDepartment of Immunology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, 28034 Madrid, Spain.ORCID 0000-0001-6124-7574
Judith VidalSection of Flow Cytometry, CATLAB, 08232 Viladecavalls, Spain.
Concepción NúñezLaboratorio de Investigación en Genética de Enfermedades Complejas, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos, 28040 Madrid, Spain.ORCID 0000-0002-9489-1603
Hospital Clínico San Carlos · ESHospital Arnau de Vilanova · ESHospital Clínico Universitario de Valladolid · ESHospital Universitario Fundación Jiménez Díaz · ESHospital Universitario Ramón y Cajal · ESInstituto de Salud Carlos III · ESInstituto Ramón y Cajal de Investigación Sanitaria · ES

Funding

Instituto de Salud Carlos III PI18/00989
6 · The paper itself

Abstract

Dermatitis herpetiformis is a cutaneous manifestation of celiac disease. Phenotyping of intraepithelial lymphocytes in the small bowel mucosa can strengthen the diagnosis of celiac disease when it is not clear-cut. We aim to evaluate the usefulness of the intraepithelial lymphogram to confirm dermatitis herpetiformis in equivocal cases. We performed a retrospective multicenter study on patients diagnosed with dermatitis herpetiformis and collected data from the intraepithelial lymphogram assessed by flow cytometry. A total of 36 patients were analyzed in relation to the severity of intestinal damage (18 had non-atrophic mucosa) at baseline (N = 28) and/or after the adoption of a gluten-free diet (median follow-up of three years, N = 16). We observed that patients with atrophy more often had positive celiac serology (

Indexed as

Anemia, Iron-DeficiencyCeliac DiseaseDermatitis HerpetiformisAtrophyData CollectionHumansRetrospective Studiesceliac diseaseceliac intraepithelial lymphogramdermatitis herpetiformisgluten-free dietT-cell flow cytometryTCRγδ+ cells

Identifiers

PMID38257124
PMCPMC10819692
OpenAlexW4390748105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.