ReviewJournal of clinical medicine2024
Prevention of Breast Cancer-Related Lymphedema: An Up-to-Date Systematic Review of Different Surgical Approaches.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Artificial Intelligence for Prediction of Breast Cancer-Related Lymphedema: A Systematic Review.Plastic and reconstructive surgery. Global open · 2026Article
- "Knockout Cancer": The Impact of Adapted Boxing Training on Quality of Life in Breast Cancer Survivors, a Case Study.Journal of functional morphology and kinesiology · 2026Article
- Development and validation of an interpretable stacking-based risk model for breast cancer- related lymphoedema: a cross-sectional study.Frontiers in oncology · 2026Article
- Factors Associated with Self-Management Behavior in Patients with Breast Cancer-Related Lymphedema.Patient preference and adherence · 2026Article
- Comprehensive overview of management and risk assessment of breast cancer-related lymphedema: a multidisciplinary approach.Frontiers in oncology · 2026Review
- Symphony of rebirth: a retrospective comparative cohort study on heterologous breast reconstruction after radiotherapy.Gland surgery · 2025Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer-related lymphedema (BCRL) affects approximately 20% of women after breast cancer therapy. Advances in treatment have increased the life expectancy; thus, the prevalence of BCRL will continue to rise with the number of cancer survivors, hence the need to develop strategies to prevent this condition. We provide a systematic review of the literature on the primary prevention of BCRL by prophylactic lymphatic surgery (PLS). Between June and August 2022, we conducted a search of PubMed, Google Scholar and Cochrane. In the end, a total of eighteen papers were selected. The eleven studies without a control group reported only 15 of 342 patients who developed lymphedema at least six months after PLS (4.59%). The seven studies with a control group included 569 patients, 328 cases and 241 controls. Among the cases, 36 (10%) developed lymphedema. In contrast, the incidence of lymphedema in the controls was 40% (98 of 241 patients). The formulation of definite recommendations in favor of PLS is hindered by low-quality studies. There is no consensus on which technique should be preferred, nor on whether adjuvant radiotherapy might affect the efficacy of PLS. Randomized controlled trials are mandatory to conceive evidence-based recommendations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.