Evidence map›Paper›PMID 38256496›Full record

ReviewJournal of clinical medicine2024

A Comprehensive Review of Risk Factors and Thrombophilia Evaluation in Venous Thromboembolism.

Andrew B Dicks, Elie Moussallem, Marcus Stanbro, Jay Walls, Sagar Gandhi, Bruce H Gray

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
29.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Guideline
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  13. The Association Study of Targeted DNA Methylation and Thrombophilia.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrew B DicksDepartment of Vascular Surgery, Prisma Health, University of South Carolina School of Medicine-Greenville, Greenville, SC 29601, USA.
Elie MoussallemDepartment of Vascular Surgery, Prisma Health, University of South Carolina School of Medicine-Greenville, Greenville, SC 29601, USA.
Marcus StanbroDepartment of Vascular Surgery, Prisma Health, University of South Carolina School of Medicine-Greenville, Greenville, SC 29601, USA.
Jay WallsDepartment of Hematology, Prisma Health, University of South Carolina School of Medicine-Greenville, Greenville, SC 29601, USA.
Sagar GandhiDepartment of Vascular Surgery, Prisma Health, University of South Carolina School of Medicine-Greenville, Greenville, SC 29601, USA.
Bruce H GrayDepartment of Vascular Surgery, Prisma Health, University of South Carolina School of Medicine-Greenville, Greenville, SC 29601, USA.ORCID 0000-0002-7321-5403
Prisma Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thromboembolism (VTE), which encompasses deep vein thrombosis (DVT) and pulmonary embolism (PE), is a significant cause of morbidity and mortality worldwide. There are many factors, both acquired and inherited, known to increase the risk of VTE. Most of these result in increased risk via several common mechanisms including circulatory stasis, endothelial damage, or increased hypercoagulability. Overall, a risk factor can be identified in the majority of patients with VTE; however, not all risk factors carry the same predictive value. It is important for clinicians to understand the potency of each individual risk factor when managing patients who have a VTE or are at risk of developing VTE. With this, many providers consider performing a thrombophilia evaluation to further define a patient's risk. However, guidance on who to test and when to test is controversial and not always clear. This comprehensive review attempts to address these aspects/concerns by providing an overview of the multifaceted risk factors associated with VTE as well as examining the role of performing a thrombophilia evaluation, including the indications and timing of performing such an evaluation.

Indexed as

deep vein thrombosispulmonary embolismrisk factorsthrombophiliavenous thromboembolism

Identifiers

PMID38256496
PMCPMC10816375
OpenAlexW4391144984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.