Evidence map›Paper›PMID 38256451›Full record

ReviewJournal of clinical medicine2024

Prone Positioning and Molecular Biomarkers in COVID and Non-COVID ARDS: A Narrative Review.

Savino Spadaro, Jose Daniel Jimenez-Santana, Riccardo La Rosa, Giorgia Spinazzola, Pilar Argente Navarro, Carlo Alberto Volta, Gaetano Scaramuzzo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Savino SpadaroDepartment of Translational Medicine, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0001-5027-5318
Jose Daniel Jimenez-SantanaDepartment of Anaesthesiology, Hospital Universitari i Politécnic la Fe, 46026 Valencia, Spain.ORCID 0009-0008-1327-0719
Riccardo La RosaDepartment of Translational Medicine, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0001-6636-960X
Giorgia SpinazzolaDepartment of Emergency, Anesthesiologic and Reanimation Sciences, Fondazione Policlinico Universitario Gemelli, IRCSS, 00168 Rome, Italy.
Pilar Argente NavarroDepartment of Anaesthesiology, Hospital Universitari i Politécnic la Fe, 46026 Valencia, Spain.
Carlo Alberto VoltaDepartment of Translational Medicine, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0003-3533-6121
Gaetano ScaramuzzoDepartment of Translational Medicine, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0001-9739-4082
University of Ferrara · ITHospital Universitari i Politècnic La Fe · ESAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prone positioning (PP) represents a therapeutic intervention with the proven capacity of ameliorating gas exchanges and ventilatory mechanics indicated in acute respiratory distress syndrome (ARDS). When PP is selectively applied to moderate-severe cases of ARDS, it sensitively affects clinical outcomes, including mortality. After the COVID-19 outbreak, clinical application of PP peaked worldwide and was applied in 60% of treated cases, according to large reports. Research on this topic has revealed many physiological underpinnings of PP, focusing on regional ventilation redistribution and the reduction of parenchymal stress and strain. However, there is a lack of evidence on biomarkers behavior in different phases and phenotypes of ARDS. Patients response to PP are, to date, decided on PaO

Indexed as

ARDSbiomarkersCOVID-19prone position

Identifiers

PMID38256451
PMCPMC10816213
OpenAlexW4390617981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.