ArticleInternational journal of molecular sciences2024
Caffeic Acid Phosphanium Derivatives: Potential Selective Antitumor, Antimicrobial and Antiprotozoal Agents.
Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Antimicrobial Properties of Freeze-Dried Hyaluronic Acid Sheets Containing Persimmon Tannin.International journal of molecular sciences · 2026Article
- Recent Developments in Ferulic Acid- and Caffeic Acid-Based Hybrids with Potential Anticancer Properties.Molecules (Basel, Switzerland) · 2026Review
- Synthesis and structure of 4-[(2,3,4,5,6-pentafluoro-phen-oxy)carbon-yl]phenyl 4-(dodec-yloxy)benzoate.Acta crystallographica. Section E, Crystallographic communications · 2026Article
- Efficacy of phosphonium amphiphilic salts against Acanthamoeba genotype T4.International journal for parasitology. Drugs and drug resistance · 2026Article
- Enhanced cytotoxic activity ofNanoscale advances · 2026Article
- Crystal structure and Hirshfeld surface studies of 4-bromo-2-chloro-phenyl (2Acta crystallographica. Section E, Crystallographic communications · 2025Article
- Crystal structure and Hirshfeld surface analysis of 4-bromo-2-chloro-phenyl (Acta crystallographica. Section E, Crystallographic communications · 2025Article
- Caffeic Acid and Erythromycin: Antibacterial and Synergistic Effects on Staphylococci.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Composition, distribution, and bioactivity of polyphenols in pineapple Fibers: Insights from UHPLC-MS analysis for the development of antibacterial materials.Current research in food science · 2025Article
- Discovery and Development of Caffeic Acid Analogs as Versatile Therapeutic Agents.Pharmaceuticals (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Caffeic acid (CA) is one of the most abundant natural compounds present in plants and has a broad spectrum of beneficial pharmacological activities. However, in some cases, synthetic derivation of original molecules can expand their scope. This study focuses on the synthesis of caffeic acid phosphanium derivatives with the ambition of increasing their biological activities. Four caffeic acid phosphanium salts (CAPs) were synthesized and tested for their cytotoxic, antibacterial, antifungal, and amoebicidal activity in vitro, with the aim of identifying the best area for their medicinal use. CAPs exhibited significantly stronger cytotoxic activity against tested cell lines (HeLa, HCT116, MDA-MB-231 MCF-7, A2058, PANC-1, Jurkat) in comparison to caffeic acid. Focusing on Jurkat cells (human leukemic T cell lymphoma), the IC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.